Azacitidine to Restore Thyroid Function in Patients With Persistent or Metastatic Thyroid Cancer
NCT00004062 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2013-12-19
Summary
RATIONALE: Azacitidine may help thyroid cancer cells regain the ability to take up iodine. This would allow the cancer to be detected and treated by radioactive iodine.
PURPOSE: Phase I trial to study the effectiveness of azacitidine to restore thyroid function in treating patients who have persistent or metastatic thyroid cancer.
Conditions
Interventions
- DRUG
- DRUG
-
liothyronine sodium
- RADIATION
-
iodine I 131
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Lucille P. Markey Cancer Center at University of Kentucky
lead OTHER
Principal Investigators
-
Kenneth Ain, MD · Lucille P. Markey Cancer Center at University of Kentucky
Study Design
- Purpose
- TREATMENT
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-07-31
- Completion
- 2006-08-31
Countries
- United States
Study Locations
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