Dasatinib in Treating Patients With Stage III Melanoma That Cannot Be Removed By Surgery or Stage IV Melanoma
NCT00436605 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 39
Last updated 2014-05-15
Summary
This phase II trial is studying how well dasatinib works in treating patients with stage III melanoma that cannot be removed by surgery or stage IV melanoma. Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Conditions
- Recurrent Melanoma
- Stage IIIA Melanoma
- Stage IIIB Melanoma
- Stage IIIC Melanoma
- Stage IV Melanoma
Interventions
- DRUG
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Harriet Kluger · Yale University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-12-31
- Primary Completion
- 2010-03-31
- Completion
- 2010-11-30
Countries
- United States
Study Locations
More Related Trials
-
Dinaciclib in Treating Patients With Stage IV Melanoma
NCT00937937 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Dinaciclib in Treating Patients With Stage III-IV Melanoma
NCT01026324 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma
NCT00509041 ·Status: COMPLETED ·Phase: PHASE2
-
Testing the Addition of the Anti-cancer Drug, Tazemetostat, to the Usual Treatment (Dabrafenib and Trametinib) for Metastatic Melanoma That Has Progressed on the Usual Treatment
NCT04557956 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Sorafenib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery
NCT00119249 ·Status: COMPLETED ·Phase: PHASE2
-
Adjuvant Dabrafenib (GSK2118436) in Patients With Surgically Resected AJCC Stage IIIC Melanoma Characterized by a BRAFV600E/K Mutation
NCT01682213 ·Status: COMPLETED ·Phase: PHASE2
-
Everolimus in Treating Patients With Stage IV Melanoma
NCT00098553 ·Status: COMPLETED ·Phase: PHASE2
-
Decitabine in Treating Patients With Melanoma or Other Advanced Cancer
NCT00002980 ·Status: COMPLETED ·Phase: PHASE1
-
MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma
NCT00866177 ·Status: COMPLETED ·Phase: PHASE2
-
Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma
NCT00121225 ·Status: COMPLETED ·Phase: PHASE2
-
ISIS 3521 in Treating Patients With Advanced, Unresectable, or Metastatic Non-small Cell Lung Cancer or Unresectable or Metastatic Melanoma
NCT00003989 ·Status: COMPLETED ·Phase: PHASE2
-
Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma
NCT01120275 ·Status: TERMINATED ·Phase: PHASE2
-
Azacitidine and Recombinant Interferon Alfa-2b in Treating Patients With Stage III or Stage IV Melanoma or Stage IV Kidney Cancer That Cannot Be Removed By Surgery
NCT00217542 ·Status: COMPLETED ·Phase: PHASE1
-
Sorafenib in Treating Patients With Advanced Malignant Solid Tumors
NCT00810394 ·Status: COMPLETED ·Phase: PHASE2
-
Treating Patients With Melanoma and ALK Alterations With Ensartinib
NCT03420508 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Evaluate RAF265, an Oral Drug Administered to Subjects With Locally Advanced or Metastatic Melanoma
NCT00304525 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction
NCT02567396 ·Status: WITHDRAWN ·Phase: PHASE1
-
Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer
NCT00004065 ·Status: COMPLETED ·Phase: PHASE1
-
Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other Cancers
NCT00498979 ·Status: COMPLETED ·Phase: PHASE1
-
Single-arm Trial to Evaluate the Biodistribution and Shedding of Talimogene Laherparepvec
NCT02014441 ·Status: COMPLETED ·Phase: PHASE2
-
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic Malignant Melanoma
NCT00104897 ·Status: COMPLETED ·Phase: PHASE2
-
Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors
NCT00859937 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Dasatinib in Advanced Sarcomas
NCT00464620 ·Status: COMPLETED ·Phase: PHASE2
-
Testing Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has Spread
NCT02196181 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of XmAb23104 in People With Sarcoma
NCT05879185 ·Status: TERMINATED ·Phase: PHASE2