Surgery With or Without Lymphadenectomy and Radiation Therapy in Treating Patients With Endometrial Cancer
NCT00003749 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 2300
Last updated 2013-12-19
Summary
RATIONALE: Lymphadenectomy may remove cancer cells that have spread to nearby lymph nodes. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether conventional surgery is more effective with or without lymphadenectomy and/or radiation therapy in treating endometrial cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of conventional surgery with or without lymphadenectomy and/or radiation therapy in treating patients who have endometrial cancer.
Conditions
Interventions
- PROCEDURE
-
adjuvant therapy
- PROCEDURE
-
conventional surgery
- RADIATION
-
brachytherapy
- RADIATION
-
radiation therapy
Sponsors & Collaborators
- lead OTHER_GOV
Principal Investigators
-
Claire Amos · Medical Research Council
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-04-30
- Completion
- 2008-12-31
Countries
- United Kingdom
Study Locations
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