Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer
NCT00003661 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 3
Last updated 2011-03-07
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Umbilical cord blood transplantation may be able to replace cells destroyed by chemotherapy or radiation therapy.
PURPOSE: Phase II trial to study the effectiveness of chemotherapy, radiation therapy, and umbilical cord blood transplantation in treating patients who have hematologic cancer.
Conditions
Interventions
- BIOLOGICAL
-
anti-thymocyte globulin
- DRUG
-
busulfan
- DRUG
-
cyclosporine
- DRUG
-
melphalan
- DRUG
-
methylprednisolone
- PROCEDURE
-
umbilical cord blood transplantation
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
Roswell Park Cancer Institute
lead OTHER
Principal Investigators
-
Barbara Jean Bambach, MD · Roswell Park Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Max Age
- 54 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-06-30
- Primary Completion
- 1999-11-30
- Completion
- 2006-03-31
Countries
- United States
Study Locations
More Related Trials
-
Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders
NCT00055653 ·Status: COMPLETED ·Phase: PHASE2
-
Pilot Study Of Unrelated UCB Transplant for Non-Malignant Hematologic Conditions
NCT00003336 ·Status: COMPLETED ·Phase: PHASE2
-
Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)
NCT00412360 ·Status: COMPLETED ·Phase: PHASE3
-
Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer
NCT00290628 ·Status: TERMINATED ·Phase: NA
-
Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer
NCT00304018 ·Status: COMPLETED ·Phase: PHASE1
-
Busulfan, Melphalan, and Antithymocyte Globulin Followed By Umbilical Cord Blood Transplant in Treating Young Patients With Refractory or Relapsed Malignant Solid Tumors
NCT00436761 ·Status: UNKNOWN ·Phase: PHASE1
-
Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer
NCT00723099 ·Status: COMPLETED ·Phase: PHASE2
-
Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood Cancers
NCT00089596 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Umbilical Cord Blood Transplantation From Unrelated Donors
NCT03016806 ·Status: RECRUITING
-
Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases
NCT00309842 ·Status: COMPLETED ·Phase: PHASE2
-
Donor Umbilical Cord Blood Transplant After Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Cancer
NCT00963872 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases
NCT01962636 ·Status: TERMINATED ·Phase: NA
-
Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematological Cancer or Other Disease
NCT00719849 ·Status: TERMINATED ·Phase: PHASE2
-
Chemotherapy and Total-Body Irradiation Followed by Donor Umbilical Cord Blood Transplant, Cyclosporine, and Mycophenolate Mofetil in Treating Patients With Hematologic Cancer
NCT00290641 ·Status: COMPLETED ·Phase: NA
-
Transplantation of Umbilical Cord Blood Following Chemotherapy for Blood Cancers
NCT00539656 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Low-Dose Fludarabine, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer
NCT00301951 ·Status: COMPLETED ·Phase: PHASE1
-
Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases
NCT06013423 ·Status: RECRUITING ·Phase: PHASE2
-
Umbilical Cord Blood and Placental Blood Transplantation in Treating Patients With Hematologic Cancer or Aplastic Anemia
NCT00008164 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluating the Safety and Effectiveness of an Umbilical Cord Blood Stem Cell Transplant (BMT CTN 0604)
NCT00864227 ·Status: COMPLETED ·Phase: PHASE2
-
Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases
NCT00376519 ·Status: TERMINATED ·Phase: PHASE1
-
Bone Marrow Transplantation in Treating Patients With Leukemia, Myelodysplasia, or Lymphoblastic Lymphoma
NCT00003187 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
NCT01093586 ·Status: COMPLETED ·Phase: PHASE2
-
Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer
NCT00281879 ·Status: TERMINATED ·Phase: PHASE2
-
Donor Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
NCT00003960 ·Status: COMPLETED ·Phase: PHASE2
-
NK Cells in Cord Blood Transplantation
NCT01619761 ·Status: UNKNOWN ·Phase: PHASE1