Donor Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
NCT00003960 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 36
Last updated 2014-05-02
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus donor bone marrow transplantation in treating patients who have hematologic cancer.
Conditions
- Leukemia
- Multiple Myeloma and Plasma Cell Neoplasm
- Myelodysplastic Syndromes
Interventions
- DRUG
-
busulfan
- DRUG
- DRUG
-
methylprednisolone
- PROCEDURE
-
allogeneic bone marrow transplantation
- PROCEDURE
-
in vitro-treated bone marrow transplantation
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
lead OTHER
Principal Investigators
-
Paul V. O'Donnell, MD, PhD · Fred Hutchinson Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 19 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-04-30
- Primary Completion
- 2001-09-30
- Completion
- 2001-09-30
Countries
- United States
Study Locations
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