Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
NCT00003624 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-04-11
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of chemotherapy.
PURPOSE: Phase II trial to study the effectiveness of amifostine in reducing the risk of side effects caused by cisplatin and paclitaxel in treating women who have ovarian, peritoneal, cervical, fallopian tube, uterine, or endometrial cancer.
Conditions
- Cervical Cancer
- Endometrial Cancer
- Fallopian Tube Cancer
- Neurotoxicity
- Ovarian Cancer
- Primary Peritoneal Cavity Cancer
- Sarcoma
Interventions
- DRUG
-
amifostine trihydrate
- DRUG
- DRUG
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Gynecologic Oncology Group
lead NETWORK
Principal Investigators
-
David H. Moore, MD · Indiana University Melvin and Bren Simon Cancer Center
Study Design
- Purpose
- SUPPORTIVE_CARE
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-12-31
- Primary Completion
- 2004-01-31
Countries
- United States
Study Locations
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