L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors
NCT00003430 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2013-06-25
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase I trial to study the effectiveness of L-778,123 in treating patients with recurrent or refractory solid tumors.
Conditions
- Head and Neck Cancer
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
L-778,123
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
David R. Spriggs, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-04-30
- Primary Completion
- 2000-04-30
- Completion
- 2000-04-30
Countries
- United States
Study Locations
More Related Trials
-
Open-Label Study to Assess the Safety/Tolerability in Patients With Solid Tumors
NCT00820560 ·Status: COMPLETED ·Phase: PHASE1
-
TTP607 in Refractory Solid Malignancies
NCT00939172 ·Status: WITHDRAWN ·Phase: PHASE1
-
Intravenous T3011 Given as a Single Agent and in Combination With Other Therapy in Subjects With Advanced Solid Tumors
NCT04780217 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors
NCT03071757 ·Status: COMPLETED ·Phase: PHASE1
-
A Dose Escalation Study of the Safety and Pharmacokinetics of GSK1363089 (Formerly XL880) Administered Orally Daily to Subjects With Solid Tumors
NCT00743067 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, PK, Dosimetry, MTD and Preliminary Efficacy of Intra-lesionally Injected AvidinOX, Followed by IV Escalating Doses of [177Lu]DOTA-biotin in Pts With Injectable Solid Tumors or Lymphomas
NCT03188328 ·Status: TERMINATED ·Phase: PHASE1
-
MSX-122 Administered Orally in Patients With Refractory Metastatic or Locally Advanced Solid Tumors
NCT00591682 ·Status: SUSPENDED ·Phase: PHASE1
-
SJG-136 in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery
NCT00121290 ·Status: COMPLETED ·Phase: PHASE1
-
Redosing With CP-870, 893 in Patients With Clinical Benefit After a Single Infusion From A Phase I, Open-Label, Dose-Escalation Study of CP-870,893 in Patients With Solid Tumors
NCT02157831 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of BKM120 Plus GSK1120212 in Selected Advanced Solid Tumor Patients
NCT01155453 ·Status: COMPLETED ·Phase: PHASE1
-
Ro 31-7453 in Treating Patients With Locally Advanced or Metastatic Solid Tumor
NCT00003755 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors
NCT06352359 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of MK0731 in Patients With Advanced Solid Tumors (0731-002)(COMPLETED)
NCT00104364 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors
NCT03510104 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Safety and Pharmacokinetics of MEGF0444A Administered to Patients With Advanced Solid Tumors
NCT00909740 ·Status: COMPLETED ·Phase: PHASE1
-
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
NCT05098132 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
KRN5500 in Treating Patients With Solid Tumors
NCT00017238 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Vorinostat in Patients With Solid Tumors (MK-0683-029)
NCT00127127 ·Status: COMPLETED ·Phase: PHASE1
-
IMX-110 in Patients With Advanced Solid Tumors
NCT03382340 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)
NCT03234712 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, PK/PD & Preliminary Efficacy of SKL27969 in Advanced Solid Tumors Patients
NCT05388435 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Dose-escalation, Dose-finding, and Expansion Study of XL495 in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06630247 ·Status: TERMINATED ·Phase: PHASE1
-
A Safety and Pharmacokinetics Study of RC220 Combined With Doxorubicin in Adult Participants With Solid Tumours.
NCT06815575 ·Status: RECRUITING ·Phase: PHASE1
-
LY293111 in Treating Patients With Advanced Solid Tumors
NCT00006375 ·Status: COMPLETED ·Phase: PHASE1
-
Talotrexin in Treating Patients With Advanced or Recurrent Solid Tumors
NCT00098514 ·Status: COMPLETED ·Phase: PHASE1