Amifostine Plus Topotecan in Treating Patients With Myelodysplastic Syndrome
NCT00003415 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 26
Last updated 2013-01-31
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy.
PURPOSE: Phase I/II trial to study the effectiveness of amifostine plus topotecan in treating patients with myelodysplastic syndrome.
Conditions
Interventions
- DRUG
-
amifostine trihydrate
- DRUG
-
topotecan hydrochloride
Sponsors & Collaborators
-
University of Arizona
lead OTHER
Principal Investigators
-
Alan F. List, MD · University of Arizona
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-09-30
- Completion
- 2002-11-30
Countries
- United States
Study Locations
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