Comparison of Combination Chemotherapy Regimens in Treating Patients With Advanced Stomach Cancer
NCT00003172 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-21
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving drugs in different combinations and combining them with interferon alfa and G-CSF may kill more tumor cells.
PURPOSE: Randomized phase II trial to compare the effectiveness of different combination chemotherapy regimens in treating patients with advanced stomach cancer.
Conditions
Interventions
- BIOLOGICAL
- BIOLOGICAL
-
recombinant interferon alfa
- DRUG
- DRUG
-
doxorubicin hydrochloride
- DRUG
- DRUG
-
hydroxyurea
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Eastern Cooperative Oncology Group
lead NETWORK
Principal Investigators
-
Scott Wadler, MD · Albert Einstein College of Medicine
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1997-12-31
- Completion
- 2004-09-30
Countries
- United States
- South Africa
Study Locations
More Related Trials
-
Combination Chemotherapy as First-Line Therapy in Treating Patients With Stage IV Gastric Cancer That Cannot Be Removed By Surgery
NCT00448682 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy Followed by Surgery in Treating Patients With Stomach Cancer
NCT00004103 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers
NCT05296005 ·Status: WITHDRAWN ·Phase: PHASE1
-
Doxorubicin, Cisplatin, 5-Fluorouracil in Patients With Advanced Adenocarcinoma of the Stomach or Esophagus
NCT00165191 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel, Oxaliplatin, and Fluorouracil in Treating Patients With Metastatic or Unresectable Stomach Cancer, Gastroesophageal Junction Cancer, or Other Solid Tumor
NCT00711243 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of Modified Docetaxel, Cisplatin, and Fluorouracil (mDCF) in Unresectable or Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma
NCT00515411 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Radiation Therapy in Treating Patients With Stomach Cancer
NCT00003862 ·Status: COMPLETED ·Phase: PHASE2
-
Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology
NCT03092518 ·Status: COMPLETED ·Phase: PHASE2
-
Aminocamptothecin in Treating Patients With Stomach Cancer or Cancer of the Esophagus
NCT00003192 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Trial of Neoadjuvant Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) With Chemoradiation
NCT04308837 ·Status: RECRUITING ·Phase: PHASE2
-
Bortezomib, Fluorouracil, and Leucovorin in Treating Patients With Metastatic or Unresectable Stomach Cancer
NCT00103103 ·Status: TERMINATED ·Phase: PHASE2
-
Trial of 4-regimen (SP, FL/Tax, FL/Doc, FOLFOX) in Patients With Recurrent or Metastatic Gastric Cancer
NCT01283204 ·Status: COMPLETED ·Phase: PHASE2
-
FOLFOX-A in the Treatment of Metastatic or Advanced Unresectable Gastric, Gastro-Esophageal Junction Adenocarcinoma
NCT03283761 ·Status: COMPLETED ·Phase: PHASE2
-
Avutometinib and Defactinib in Diffuse Gastric Cancer
NCT06487221 ·Status: RECRUITING ·Phase: PHASE2
-
Phase II Study of Oxaliplatin, Irinotecan, and Capecitabine in Advanced Gastric/Gastroesophageal Junction Carcinoma
NCT00084617 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel and S-1 Combination Therapy as Second-line Treatment for Advanced Gastric Cancer
NCT03137004 ·Status: UNKNOWN ·Phase: PHASE2
-
Trial of Adjuvant Chemotherapy for Gastric Cancer
NCT00296335 ·Status: COMPLETED ·Phase: PHASE3
-
Intergroup Trial of Adjuvant Chemotherapy in Adenocarcinoma of the Stomach
NCT01640782 ·Status: COMPLETED ·Phase: PHASE3
-
Chemotherapy Options for the First Line Chemotherapy in Elderly Patient With Advanced Gastric Cancer
NCT02114359 ·Status: COMPLETED ·Phase: PHASE3
-
Multicenter Study to Perioperative Chemotherapy for Resectable Adenocarcinoma in Gastric Cancer
NCT01160419 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Trial Evaluating FOLFIRI + Durvalumab vs FOLFIRI + Durvalumab and Tremelimumab in Second-line Treatment of Patients With Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma
NCT03959293 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Metronomic Chemotherapy in Advanced Gastric Cancer
NCT02855788 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemotherapy and Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Stomach Who Have Undergone Surgery
NCT00011960 ·Status: COMPLETED ·Phase: PHASE2
-
Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
NCT05702229 ·Status: RECRUITING ·Phase: PHASE2
-
Preoperative Chemo and Chemoradiotherapy for Adenocarcinoma of the Stomach and Gastroesophageal Junction (GEJ)
NCT00525785 ·Status: COMPLETED ·Phase: PHASE2