Combination Chemotherapy and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia
NCT00002598 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2013-06-25
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. Interferon alfa may interfere with the growth of cancer cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy and interferon alfa in treating patients with chronic myelogenous leukemia.
Conditions
Interventions
- BIOLOGICAL
-
recombinant interferon alfa
- BIOLOGICAL
-
sargramostim
- DRUG
- DRUG
- DRUG
-
etoposide
- DRUG
-
methotrexate
- DRUG
-
mitoxantrone hydrochloride
- PROCEDURE
-
bone marrow ablation with stem cell support
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Mark Adam Weiss, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 16 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1994-06-30
- Primary Completion
- 2004-06-30
- Completion
- 2004-06-30
Countries
- United States
Study Locations
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