Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia
NCT00002531 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-09-17
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
PURPOSE: Randomized phase II trial to study the effectiveness of various combination chemotherapy regimens in treating patients with acute lymphocytic leukemia.
Conditions
Interventions
- DRUG
-
asparaginase
- DRUG
- DRUG
- DRUG
-
daunorubicin hydrochloride
- DRUG
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
etoposide
- DRUG
-
ifosfamide
- DRUG
-
leucovorin calcium
- DRUG
-
mercaptopurine
- DRUG
-
methotrexate
- DRUG
-
mitoxantrone hydrochloride
- DRUG
-
prednisolone
- DRUG
-
teniposide
- DRUG
-
thioguanine
- DRUG
-
vincristine sulfate
- DRUG
-
vindesine
- PROCEDURE
-
allogeneic bone marrow transplantation
- PROCEDURE
-
peripheral blood stem cell transplantation
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
Johann Wolfgang Goethe University Hospital
lead OTHER
Principal Investigators
-
Dieter Hoelzer, MD, PhD · Johann Wolfgang Goethe University Hospital
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 15 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1993-01-31
Countries
- Germany
Study Locations
More Related Trials
-
Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
NCT00002805 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia
NCT00002658 ·Status: UNKNOWN ·Phase: PHASE3
-
Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment
NCT02881086 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia
NCT00022126 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
NCT00408005 ·Status: COMPLETED ·Phase: PHASE3
-
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)
NCT00199069 ·Status: COMPLETED ·Phase: PHASE4
-
Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
NCT00002471 ·Status: COMPLETED ·Phase: PHASE2
-
Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement
NCT02828358 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00016302 ·Status: COMPLETED ·Phase: NA
-
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00103285 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
NCT00002798 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma
NCT00002766 ·Status: COMPLETED ·Phase: PHASE3
-
Multicenter Study of Combined Chemotherapy and Transplantation for Adult ALL
NCT07059156 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
Combination Chemotherapy Plus Infusion of White Blood Cells in Treating Patients With Hematologic Cancer
NCT00003243 ·Status: COMPLETED ·Phase: PHASE1
-
S0333 Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00109837 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia
NCT00343369 ·Status: UNKNOWN ·Phase: NA
-
Combination Chemotherapy in Treating Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT01005758 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy of 5-azacytidine Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)
NCT00915252 ·Status: COMPLETED ·Phase: PHASE2
-
Azacitidine in Combination With Mitoxantrone, Etoposide Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
NCT01249430 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia
NCT03488225 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With AML Leukemia
NCT00049517 ·Status: COMPLETED ·Phase: PHASE3
-
High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
NCT00002865 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia
NCT00199095 ·Status: COMPLETED ·Phase: PHASE4
-
Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Acute Myelogenous Leukemia
NCT00002549 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia
NCT00003700 ·Status: COMPLETED ·Phase: PHASE2