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Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS)

NCT00000541 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL

Last updated 2020-07-15

No results posted yet for this study

Summary

To determine if supplements of vitamin C, vitamin E, beta-carotene, and B-vitamins (a combination of folic acid, vitamins B6 and B12) reduce risk of major cardiovascular events in high risk women with a prior history of atherosclerotic cardiovascular disease. The trial is a companion to the Women's Health Study (WHS), a primary prevention trial of vitamin E and aspirin in a low risk population of women.

Conditions

Interventions

BEHAVIORAL

dietary supplements

DRUG

vitamin C

DRUG

vitamin E

DRUG

beta-carotene

DRUG

folic acid/Vitamin B6/Vitamin B12

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • Brigham and Women's Hospital

    lead OTHER

Principal Investigators

  • JoAnn Manson · Brigham and Women's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Model
FACTORIAL

Eligibility

Min Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
1993-05-31
Primary Completion
2005-07-31
Completion
2005-07-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00000541 on ClinicalTrials.gov