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Asymptomatic Carotid Artery Plaque Study (ACAPS)

NCT00000469 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL

Last updated 2016-05-13

No results posted yet for this study

Summary

To determine whether warfarin or lovastatin alone or in combination retarded the progression of atherosclerotic plaques in the carotid arteries of high risk individuals with asymptomatic carotid stenosis. Also, to determine if a full scale trial was feasible.

Conditions

  • Cardiovascular Diseases
  • Carotid Stenosis
  • Cerebral Arteriosclerosis
  • Cerebrovascular Disorders
  • Heart Diseases
  • Vascular Diseases

Interventions

DRUG

aspirin

DRUG

lovastatin

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    lead NIH

Principal Investigators

  • Mark Espeland · Bowman Gray School of Medicine

  • Curt Furberg · Bowman Gray School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE

Eligibility

Min Age
40 Years
Max Age
79 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1988-05-31
Completion
1998-08-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00000469 on ClinicalTrials.gov