NCT05091528 A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers Status TERMINATED Phase PHASE1/PHASE2
NCT05081609 A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05076695 Neoadjuvant With Trastuzumab, Pyrotinib Plus Palbociclib and Fulvestrant in HER2-positive, ER-positive Breast Cancer Status UNKNOWN Phase PHASE2
NCT05063786 Trastuzumab + Alpelisib +/- Fulvestrant vs Trastuzumab + CT in Patients With PIK3CA Mutated Previously Treated HER2+ Advanced BrEasT Cancer (ALPHABET) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05062889 Exploiting Circulating Tumour DNA to Intensify the Postoperative Treatment Resected Colon Cancer Patients Status SUSPENDED Phase PHASE2
NCT05041842 Treatment With Tucatinib in Patients With an Isolated Brain Progression of a Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05020860 Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer Status RECRUITING Phase PHASE2
NCT05002127 A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06) Status ACTIVE_NOT_RECRUITING Phase PHASE2/PHASE3
NCT04993014 Circulating Tumor Cells and Treatment De-escalation After Neoadjuvant Therapy for HER2 Positive Breast Cancer Status RECRUITING Phase PHASE2
NCT04973319 Trastuzumab Combined With Pertuzumab for Adjuvant Treatment of Breast Cancer After Neoadjuvant Therapy Status NOT_YET_RECRUITING Phase PHASE3
NCT04962425 Risk Assessment Model of Trastuzumab-related Cardiotoxicity in Breast Cancer Patients Status UNKNOWN Phase N/A
NCT04961307 Evaluation of Heart Function in Breast Cancer Patients Using Trastuzumab Status UNKNOWN Phase N/A
NCT04957212 Comparing Efficacy and Safety Between Pertuzumab® and Perjeta® in Neoadjuvant Treatment of HER2+ Breast Cancer Status COMPLETED Phase PHASE3
NCT04928261 Evaluating 6-months of HER2-targeted Therapy in Patients With HER2 Positive Early-stage Breast Cancer That Achieve a Pathological Complete Response to Neoadjuvant Systemic Therapy Status ACTIVE_NOT_RECRUITING Phase PHASE4
NCT04908813 Study of HLX22 in Combanition With Trastuzumab and Chemotherapy Versus Placebo in Combination With Trastuzumab and Chemotherapy for Treatment of Locally Advanced or Metastatic Gastric Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04886531 Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers Status RECRUITING Phase PHASE2
NCT04873362 A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04819971 Study of Perioperative Chemotherapy Combined With Tislelizumab and Trastuzumab in the Treatment of GC/EGC Status RECRUITING Phase PHASE2
NCT04784715 Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09) Status ACTIVE_NOT_RECRUITING Phase PHASE3