NCT04760431 TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN) Status UNKNOWN Phase PHASE2
NCT04721977 A Study of Tucatinib (MK-7119) in Combination With Trastuzumab and Capecitabine in Participants With Previously Treated Locally Advanced Unresectable or Metastatic Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Breast Carcinoma (MK-7119-001) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04717531 Pyrotinib as Neoadjuvant Agent for Non-objective Response HER2-positive Early Breast Cancer Status UNKNOWN Phase PHASE2
NCT04683445 Efficacy and Safety of Eribulin in the Treatment of Advanced Breast Cancer Status UNKNOWN Phase N/A
NCT04680442 Safety of Continuing HER-2 Directed Therapy in Overt Left Ventricular Dysfunction Status RECRUITING Phase PHASE2
NCT04661150 A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal Junction Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04639271 Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain Metastasis Status UNKNOWN Phase PHASE2
NCT04629846 Study in Participants With Early-Stage or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive and Estrogen Receptor/Progesterone Receptor Negative Breast Cancer to Evaluate the Efficiency and Safety of Treatment With Trastuzumab Plus (+) QL1209/Pertuzumab + Docetaxel. Status COMPLETED Phase PHASE3
NCT04609540 Pyrotinib Combined With Trastuzumab And Chemotherapy in HER2-positive MBC Status UNKNOWN Phase N/A
NCT04591431 The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04588545 Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04579380 Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04512261 TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain Metastases Status WITHDRAWN Phase PHASE1/PHASE2
NCT04510285 A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection Status TERMINATED Phase PHASE2
NCT04499924 Tucatinib, Trastuzumab, Ramucirumab, and Paclitaxel Versus Paclitaxel and Ramucirumab in Previously Treated HER2+ Gastroesophageal Cancer Status COMPLETED Phase PHASE2/PHASE3
NCT04464967 Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers Status WITHDRAWN Phase PHASE1/PHASE2
NCT04430738 Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04419181 Feasibility of Chemotherapy De-escalation in Early-Stage HER2 Positive Breast Cancer Status WITHDRAWN Phase PHASE2