NCT03248427 Neadjuvant Multi-agent Chemotherapy or Letrozole Plus Ribociclib in Luminal B/HER2-negative Breast Cancer. Status COMPLETED Phase PHASE2
NCT03237390 Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors Status COMPLETED Phase PHASE1
NCT03179956 Impact of Ribociclib on Head and Neck Squamous Cell Cancer Status TERMINATED Phase EARLY_PHASE1
NCT03114527 Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT03096912 A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma Status UNKNOWN Phase PHASE2
NCT03096847 Study for Women and Men With Hormone-receptor Positive Locally Advanced or Metastatic Breast Cancer Status COMPLETED Phase PHASE3
NCT03081234 Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- Intermediate Risk Early Breast Cancer Status WITHDRAWN Phase PHASE3
NCT03078751 Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- High Risk Early Breast Cancer Status COMPLETED Phase PHASE2
NCT03056833 Ribociclib (Ribociclib (LEE-011)) With Platinum-based Chemotherapy in Recurrent Platinum Sensitive Ovarian Cancer Status COMPLETED Phase PHASE1
NCT03050398 A Companion Sample Collection Protocol to Support the Discovery of Breast Cancer Aberrations With Treatment of CDK4/6 Therapy/LEE011/Ribociclib Status TERMINATED Phase PHASE3
NCT03009201 Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery Status COMPLETED Phase PHASE1
NCT03008408 A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT02974725 A Phase Ib Study of LXH254-centric Combinations in NSCLC or Melanoma Status TERMINATED Phase PHASE1
NCT02941926 Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC Status COMPLETED Phase PHASE3
NCT02933736 Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients Status ACTIVE_NOT_RECRUITING Phase EARLY_PHASE1
NCT02813135 European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT02732119 Study of Ribociclib With Everolimus + Exemestane in HR+ HER2- Locally Advanced/Metastatic Breast Cancer Post Progression on CDK 4/6 Inhibitor. Status COMPLETED Phase PHASE1/PHASE2