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NCT07492641 BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease Status RECRUITING Phase PHASE3
NCT07487129 Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt Status COMPLETED Phase PHASE4
NCT07405801 A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer Status RECRUITING Phase PHASE2
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NCT07174336 A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA) Status RECRUITING Phase PHASE3
NCT07085767 Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer Status RECRUITING Phase PHASE3
NCT07054190 A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer Status RECRUITING Phase PHASE2
NCT06930859 Non-interventional Study to Assess the Effectiveness and Safety of Ribociclib in the Adjuvant Therapy of Hormone Receptor Positive (HR+) HER2-negative Stage II and III Breast Cancer in Real Clinical Practice in Russia Status RECRUITING Phase N/A
NCT06905301 Implementation Study to Describe and Compare Retention Rate and Adherence to Adjuvant Therapy With Ribociclib With and Without Usage of Mobile Application in Patients With HR+ HER2-negative Stage II and III Breast Cancer in Real-world Practice Status RECRUITING Phase N/A
NCT06805812 Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study Status RECRUITING Phase N/A
NCT06797531 RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia Status RECRUITING Phase N/A
NCT06760637 Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT06726148 Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT06625775 Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors Status RECRUITING Phase PHASE1
NCT06587789 Ribociclib in Combination With Adjuvant Endocrine Therapy for Patients With Early High-risk HR+HER2- Breast Cancer Status RECRUITING Phase N/A
NCT06495164 A Real-life Study to Understand the Use and Effects of Palbociclib in US Patients With Breast Cancer Status ACTIVE_NOT_RECRUITING Phase N/A
NCT06409390 Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer Status RECRUITING Phase PHASE2
NCT06380751 Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer Status RECRUITING Phase PHASE3