NCT04220892 Pilot Study of Pembrolizumab Combined With Pemetrexed or Abemaciclib for High Grade Glioma Status WITHDRAWN Phase EARLY_PHASE1
NCT04220866 Study of Intratumoral (IT) Ulevostinag (MK-1454) in Combination With Intravenous (IV) Pembrolizumab (MK-3475) Compared to IV Pembrolizumab Alone as the First Line Treatment of Metastatic or Unresectable, Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) (MK-1454-002) Status COMPLETED Phase PHASE2
NCT04216316 Testing the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04214249 BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04214067 Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04211103 Pembrolizumab in Pre Neoplastic High Grade HPV-related Vulvar and Cervical Lesions Status UNKNOWN Phase PHASE2
NCT04210115 Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04209686 Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04209660 Lenvatinib and Pembrolizumab in People With Advanced Adenoid Cystic Carcinoma and Other Salivary Gland Cancers Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04207086 A Phase II Study of Neoadjuvant Pembrolizumab & Lenvatinib for Resectable Stage III Melanoma Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04205227 ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04201873 Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04199104 A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010) (KEYNOTE-010) Status COMPLETED Phase PHASE3
NCT04197219 Pembrolizumab With Axitinib in Recurrent Endometrial Cancer Status WITHDRAWN Phase PHASE2
NCT04194944 A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04193293 A Study of Duvelisib in Combination With Pembrolizumab in Head and Neck Cancer Status TERMINATED Phase PHASE1/PHASE2
NCT04191135 Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009) Status COMPLETED Phase PHASE2
NCT04191096 Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991) Status COMPLETED Phase PHASE3
NCT04190056 Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer Status TERMINATED Phase PHASE2