NCT03776136 Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) for Advanced Melanoma in Anti-Programmed Death-1/Programmed Death-Ligand 1 (PD-1/L1)-Exposed Participants (MK-7902-004/E7080-G000-225/LEAP-004) Status COMPLETED Phase PHASE2
NCT03775707 Lenvatinib Plus PD-1 Antibody for Intermediate-stage HCC Beyond Up-to-seven Criteria Status WITHDRAWN Phase PHASE2
NCT03744247 Lenvatinib Plus PD-1 Antibody Versus Lenvtinib Alone for Advanced HCC Status WITHDRAWN Phase PHASE3
NCT03713593 Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) Versus Lenvatinib as First-line Therapy in Participants With Advanced Hepatocellular Carcinoma (MK-7902-002/E7080-G000-311/LEAP-002) Status COMPLETED Phase PHASE3
NCT03663114 A Post-marketing Observational Study on Risk Factors for Hepatic Encephalopathy in Participants With Unresectable Hepatocellular Carcinoma Status COMPLETED Phase N/A
NCT03630120 Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer Status TERMINATED Phase PHASE2
NCT03609359 Lenvatinib and Pembrolizumab Simultaneous Combination Study Status COMPLETED Phase PHASE2
NCT03573960 A Study to Evaluate the Safety and Efficacy of Lenvatinib in Participants With Refractory Differentiated Thyroid Cancer Status COMPLETED Phase PHASE4
NCT03564691 Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001) Status COMPLETED Phase PHASE1
NCT03533361 Expanded Access Program With Lenvatinib for the Treatment of Differentiated Thyroid Cancer in Brazil Status APPROVED_FOR_MARKETING Phase N/A
NCT03526679 Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma Status COMPLETED Phase PHASE1/PHASE2
NCT03517449 Lenvatinib in Combination With Pembrolizumab Versus Treatment of Physician's Choice in Participants With Advanced Endometrial Cancer (MK-3475-775/E7080-G000-309 Per Merck Standard Convention [KEYNOTE-775]) Status COMPLETED Phase PHASE3
NCT03516981 A Study of Biomarker-Directed, Pembrolizumab (MK-3475) Based Combination Therapy for Advanced Non-Small Cell Lung Cancer (MK-3475-495/KEYNOTE-495) Status COMPLETED Phase PHASE2
NCT03506048 Lenvatinib and Iodine Therapy in Treating Patients With Radioactive Iodine-Sensitive Differentiated Thyroid Cancer Status TERMINATED Phase PHASE2
NCT03486873 Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587) Status RECRUITING Phase PHASE3
NCT03433703 Trial to Evaluate Safety and Efficacy of Treatment of Physician Choice (TPC) Following First-Line Treatment of Lenvatinib in Subjects With Unresectable Hepatocellular Carcinoma (uHCC) Status TERMINATED Phase PHASE2
NCT03418922 A Study of Lenvatinib Plus Nivolumab in Participants With Hepatocellular Carcinoma Status COMPLETED Phase PHASE1