NCT06047184 Phase I Study of BEBT-209 in Women With Advanced Breast Cancer Status UNKNOWN Phase PHASE1
NCT06016738 OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer Status RECRUITING Phase PHASE3
NCT05963984 A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult Participants Status COMPLETED Phase PHASE2
NCT05933395 Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor Status RECRUITING Phase PHASE2
NCT05870579 [177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT05867251 Study of AVZO-021 in Patients With Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT05806671 Dalpiciclib Plus Fulvestrant With Pyrotinib in Hormone Receptor-positive, HER2-low Advanced Breast Cancer That Progressed on Previous CDK4/6i Plus AI Therapy Status NOT_YET_RECRUITING Phase PHASE2
NCT05768139 First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT05759949 First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors Status COMPLETED Phase PHASE1
NCT05735080 Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer Status RECRUITING Phase PHASE1/PHASE2
NCT05720260 Immunotherapy, Hormone Therapy, and AKT Inhibitor for Premenopausal ER Positive MBC Status RECRUITING Phase PHASE2
NCT05683418 A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer Status RECRUITING Phase PHASE1
NCT05654623 A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05646862 A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05631795 Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment Status COMPLETED Phase PHASE4
NCT05601440 Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer Status RECRUITING Phase PHASE2
NCT05577923 Exploring Whether Disease-free Intervals Can Guide Endocrine Combined Targeted Therapy for ER+/HER2+ Advanced Breast Cancer (T-sunflower) Status NOT_YET_RECRUITING Phase PHASE2
NCT05574881 Dalpiciclib, Fulvestrant, Trastuzumab and Pertuzumab in HR Positive, HER2 Positive Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05573126 Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer Status RECRUITING Phase PHASE1/PHASE2