NCT05564377 Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial Status RECRUITING Phase PHASE2
NCT05554354 Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial) Status TERMINATED Phase PHASE2
NCT05536128 Evaluating the Efficacy and Safety of Fulvestrant Plus DNA Damage Repair Inhibitors After a CDK4/6 Inhibitor Status RECRUITING Phase PHASE2
NCT05524584 Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer Status RECRUITING Phase PHASE2
NCT05501886 Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05467891 Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer Status RECRUITING Phase PHASE2
NCT05433480 A Study of BPI-16350 in Combination With Fulvestrant in Patients With HR+ and HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer Status UNKNOWN Phase PHASE3
NCT05392608 SEQUence of Endocrine Therapy in Advanced Luminal Breast Cancer (SEQUEL-Breast) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05384119 Phase 1b/2 Study of TTI-101 in Combination for Patients With Metastatic Hormone Receptor-Positive and HER2-Negative Breast Cancer Status TERMINATED Phase PHASE1
NCT05328440 Treatment of Dalpiciclib Combined With Pyrotinib for Trastuzumab-sensitive HER2+ Advanced Breast Cancer(DAP-Her-02) Status RECRUITING Phase PHASE2
NCT05319873 Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05307705 A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors Status RECRUITING Phase PHASE1
NCT05306340 A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05251714 CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05238922 Study of INCB123667 in Subjects With Advanced Solid Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT05230810 Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer. Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05226871 Study for Participants Continuing From Pfizer-sponsored Palbociclib (a Study Medicine) Studies Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05216432 First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer Status RECRUITING Phase PHASE1