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NCT06578559 Phase II Study of ctDNA-guided Encorafenib Plus Cetuximab Retreatment in Patients BRAF V600E Mutated mCRC Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT06194929 Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma Status RECRUITING Phase PHASE1/PHASE2
NCT06102902 Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer Status SUSPENDED Phase PHASE1
NCT05985954 Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy Status RECRUITING Phase PHASE1
NCT05926960 A Study Comparing 3 Study Medicines (Encorafenib, Binimetinib, Pembrolizumab) to 2 Study Medicines (Ipilimumab and Nivolumab) in Patients With Advanced Melanoma Status TERMINATED Phase PHASE2
NCT05743036 ZN-c3 in Adult Participants With Metastatic Colorectal Cancer Status TERMINATED Phase PHASE1
NCT05725200 Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer Status RECRUITING Phase PHASE2
NCT05710406 Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2/PHASE3
NCT05615818 Personalized Medicine for Advanced Biliary Cancer Patients Status RECRUITING Phase PHASE3
NCT05308446 Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05304546 Overcoming Primary Resistance to Immunotherapy in Metastatic Melanoma Status COMPLETED Phase PHASE2
NCT05260684 Comparative Effectiveness of Targeted Therapies in BRAF Positive Metastatic Melanoma in the US Status COMPLETED Phase N/A
NCT05217446 A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05195632 Phase II Study Investigating the Combination of Encorafenib and Binimetinib in BRAF V600E Mutated Chinese Patients With Metastatic Non-Small Cell Lung Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05039177 A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies Status COMPLETED Phase PHASE1/PHASE2
NCT05026983 Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases Status RECRUITING Phase PHASE2
NCT05004350 A Study Evaluating the Combination of Encorafenib and Cetuximab Versus Irinotecan/Cetuximab or Infusional 5-fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab in Chinese Patients With BRAF V600E Mutant Metastatic Colorectal Cancer. Status COMPLETED Phase PHASE2
NCT05003622 Phase 1 Safety Study of Encorafenib in Chinese Patients With Advanced Metastatic BRAF V600E Mutant Solid Tumors Status COMPLETED Phase PHASE1