Elahere (mirvetuximab soravtansine-gynx) is an FDA-approved folate receptor-alpha-directed antibody-drug conjugate for FRα-positive platinum-resistant ovarian-related cancers after prior systemic treatment. It is administered intravenously every 3 weeks with mandatory eye-care precautions because of ocular toxicity risk. Initial U.S. approval was in 2022 and labeling is updated through 2025.
Drug Class
Folate receptor-alpha (FRalpha)-directed antibody and microtubule inhibitor conjugate
Approval Status
FDA approved (initial U.S. approval 2022; labeling revised July 2025)
Brand Names
ELAHERE
Indications
\FRalpha-positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer in adults after one to three prior systemic treatment regimens\
AbbVie raised 2026 revenue and EPS guidance after first-quarter results beat estimates, with Skyrizi and Rinvoq driving growth. Humira erosion continued as neuroscience, oncology and pipeline assets supported the outlook.
Eli Lilly, AbbVie, Vertex, Gilead Sciences and Pfizer were identified as pharmaceutical stocks to watch, with Abbott Laboratories and McKesson appearing on a separate seven-stock list.
AbbVie said Skyrizi and Rinvoq generated $26.0 billion in 2025 sales and are expected to exceed $31 billion in 2026. The company said the two immunology drugs continue to offset Humira erosion and drive top-line growth.
The FDA has approved Lifyorli (relacorilant) plus nab-paclitaxel for platinum-resistant ovarian cancer based on trial data showing improved survival. Separately, the agency granted Breakthrough Therapy designation to Lilly's sofetabart mipitecan for the same condition, expediting development of the antibody-drug conjugate.
AbbVie has successfully transitioned from Humira dependence to growth driven by Skyrizi and Rinvoq, while maintaining a 54-year dividend increase streak and expanding its pipeline to roughly 90 programs through strategic acquisitions.
AbbVie projects 43-45% earnings growth in 2026 as newer immunology drugs Skyrizi and Rinvoq offset declining Humira sales, while maintaining its 54-year dividend increase streak as a Dividend King.