Elahere

Drug

Also known as: Elahere

Drug Profile

Elahere (mirvetuximab soravtansine-gynx) is an FDA-approved folate receptor-alpha-directed antibody-drug conjugate for FRα-positive platinum-resistant ovarian-related cancers after prior systemic treatment. It is administered intravenously every 3 weeks with mandatory eye-care precautions because of ocular toxicity risk. Initial U.S. approval was in 2022 and labeling is updated through 2025.

Drug Class
Folate receptor-alpha (FRalpha)-directed antibody and microtubule inhibitor conjugate
Approval Status
FDA approved (initial U.S. approval 2022; labeling revised July 2025)
Brand Names
  • ELAHERE
Indications
  • \FRalpha-positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer in adults after one to three prior systemic treatment regimens\

Related News

FDA Approves Lifyorli Plus Nab-Paclitaxel for Platinum-Resistant Ovarian Cancer

The FDA has approved Lifyorli (relacorilant) plus nab-paclitaxel for platinum-resistant ovarian cancer based on trial data showing improved survival. Separately, the agency granted Breakthrough Therapy designation to Lilly's sofetabart mipitecan for the same condition, expediting development of the antibody-drug conjugate.