Elahere

Drug

Also known as: Elahere

Drug Profile

Elahere (mirvetuximab soravtansine-gynx) is an FDA-approved folate receptor-alpha-directed antibody-drug conjugate for FRα-positive platinum-resistant ovarian-related cancers after prior systemic treatment. It is administered intravenously every 3 weeks with mandatory eye-care precautions because of ocular toxicity risk. Initial U.S. approval was in 2022 and labeling is updated through 2025.

Drug Class
Folate receptor-alpha (FRalpha)-directed antibody and microtubule inhibitor conjugate
Approval Status
FDA approved (initial U.S. approval 2022; labeling revised July 2025)
Brand Names
  • ELAHERE
Indications
  • \FRalpha-positive, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer in adults after one to three prior systemic treatment regimens\

Related News

Breakthrough ovarian cancer drug mirvetuximab soravtansine now available on NHS

A breakthrough ovarian cancer drug, mirvetuximab soravtansine, is now available on the NHS, offering extended survival and improved quality of life. The 'biological missile' therapy targets cancer cells directly, reducing side-effects compared to standard chemotherapy. Up to 400 patients in England could benefit each year.

FDA Approves Lifyorli Plus Nab-Paclitaxel for Platinum-Resistant Ovarian Cancer

The FDA has approved Lifyorli (relacorilant) plus nab-paclitaxel for platinum-resistant ovarian cancer based on trial data showing improved survival. Separately, the agency granted Breakthrough Therapy designation to Lilly's sofetabart mipitecan for the same condition, expediting development of the antibody-drug conjugate.