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NCT03722329 Pharmacokinetic, Safety, Tolerability, Immunogenicity, and Pharmacodynamic Study of SB12 in Healthy Subjects Status COMPLETED Phase PHASE1
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NCT03472885 Study of Danicopan in Participants With Paroxysmal Nocturnal Hemoglobinuria With Inadequate Response to Eculizumab Status COMPLETED Phase PHASE2
NCT03468140 Pilot Trial of Eculizumab Therapy to Reduce Preservation Injury in Human Macrosteatotic Liver Transplantation Status WITHDRAWN Phase EARLY_PHASE1
NCT03056040 ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab Status COMPLETED Phase PHASE3
NCT02946463 ALXN1210 (Ravulizumab) Versus Eculizumab in Complement Inhibitor Treatment-Naïve Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Status COMPLETED Phase PHASE3
NCT02727608 Complement Inhibitor Eculizumab in Clinical Islet Transplantation Status COMPLETED Phase PHASE2
NCT02604420 Identification and Treatment of Thrombotic Microangiopathies in Allogeneic Stem Cell Transplants Status COMPLETED Phase N/A
NCT02574403 Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS Status COMPLETED Phase PHASE4
NCT02301624 Extension Study of ECU-MG-301 to Evaluate Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis Status COMPLETED Phase PHASE3
NCT02298933 Complement Inhibition Using Eculizumab to Overcome Platelet Transfusion Refractoriness in Patients With Severe Thrombocytopenia Status COMPLETED Phase PHASE2
NCT02205541 Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU Status COMPLETED Phase PHASE3
NCT02145182 Prevention of Delayed Graft Function Using Eculizumab Therapy (PROTECT Study) Status COMPLETED Phase PHASE2/PHASE3