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NCT05133531 A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05131204 Efficacy and Safety of the Combination of Pozelimab and Cemdisiran Versus Continued Eculizumab or Ravulizumab Treatment in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria Status TERMINATED Phase PHASE3
NCT05116774 BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor Therapy Status TERMINATED Phase PHASE2
NCT04935177 Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx Status COMPLETED Phase PHASE3
NCT04752566 A Study to Evaluate the Efficacy and Safety of Eculizumab in Guillain-Barré Syndrome Status COMPLETED Phase PHASE3
NCT04725812 Complement Regulation to Undo Systemic Harm in Preeclampsia Status TERMINATED Phase PHASE2
NCT04702568 A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Status TERMINATED Phase PHASE2
NCT04558918 Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment Status COMPLETED Phase PHASE3
NCT04434092 A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04432584 A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04355494 SOLIRIS® (Eculizumab) Treatment of Participants With COVID-19 Status NO_LONGER_AVAILABLE Phase N/A
NCT04346797 CORIMUNO19-ECU: Trial Evaluating Efficacy and Safety of Eculizumab (Soliris) in Patients With COVID-19 Infection, Nested in the CORIMUNO-19 Cohort Status UNKNOWN Phase PHASE2