News Related to Psychiatric Conditions

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Lipocine's Oral PPD Drug LPCN 1154 Misses Phase 3 Primary Endpoint

Apr 02, 2026

Lipocine's oral postpartum depression drug LPCN 1154 failed to meet its primary endpoint in a Phase 3 trial involving 90 patients. However, a post hoc analysis showed clinically meaningful improvements in a subset of 54 patients with psychiatric history, and the drug demonstrated a favorable safety profile supporting outpatient use.