Postpartum depression is a mood disorder occurring after childbirth, characterized by persistent depressive symptoms that impair maternal functioning and can affect infant and family outcomes.
FDA final guidance sets standards for psychedelic clinical trials. Federal agencies and states are advancing psilocybin and ibogaine research, and Eli Lilly is acquiring AtaiBeckley for $2.8 billion.
A new study reveals that a second pregnancy uniquely alters the female brain, with distinct changes in attention and sensory networks compared to the first pregnancy. The research also links brain changes to mother-child bonding and peripartum depression.
Lipocine's oral postpartum depression drug LPCN 1154 failed to meet its primary endpoint in a Phase 3 trial involving 90 patients. However, a post hoc analysis showed clinically meaningful improvements in a subset of 54 patients with psychiatric history, and the drug demonstrated a favorable safety profile supporting outpatient use.
Recent studies reveal significant barriers in accessing mental health care for children and maternal health services, with nearly 25% of children's mental health needs going unmet and abortion restrictions linked to increased maternal deaths.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07747285 |
POSH-Ex: Physiotherapist-Led Telerehabilitation Exercise Programme for Postpartum Sexual Health |
NOT_YET_RECRUITING | NA |
| NCT07647809 |
Clinical Pilates and Prenatal Education on Perinatal Depressive Symptoms |
COMPLETED | NA |
| NCT07639099 |
Intranasal Esketamine-dexmedetomidine Combination and Postpartum Depression |
NOT_YET_RECRUITING | PHASE4 |
| NCT07636005 |
Psychological Empowerment Program in Preventing Postpartum Depression Among Pregnant Women |
ACTIVE_NOT_RECRUITING | NA |
| NCT07603063 |
A Descriptive Study of the Correlation Between Postpartum Depression and Body Image Dissatisfaction, Self-objectification, and Social Media Appearance Comparison |
NOT_YET_RECRUITING | |
| NCT07523932 |
Midwife-Led Digital Follow-Up After Cesarean Section |
NOT_YET_RECRUITING | NA |
| NCT07515222 |
Efficacy of Yoga-Based Intervention in Improving Mother-Child Bonding in Maternal Depression |
NOT_YET_RECRUITING | NA |
| NCT07506759 |
The Effect of Psychodramatic Role-Playing on Postpartum Depression, Self-Efficacy, and Perceived Social Support |
COMPLETED | NA |
| NCT07398469 |
A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone |
RECRUITING | |
| NCT07354334 |
Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outcomes |
ENROLLING_BY_INVITATION | NA |
