Postpartum depression is a mood disorder occurring after childbirth, characterized by persistent depressive symptoms that impair maternal functioning and can affect infant and family outcomes.
Lipocine's oral postpartum depression drug LPCN 1154 failed to meet its primary endpoint in a Phase 3 trial involving 90 patients. However, a post hoc analysis showed clinically meaningful improvements in a subset of 54 patients with psychiatric history, and the drug demonstrated a favorable safety profile supporting outpatient use.
Recent studies reveal significant barriers in accessing mental health care for children and maternal health services, with nearly 25% of children's mental health needs going unmet and abortion restrictions linked to increased maternal deaths.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07603063 |
A Descriptive Study of the Correlation Between Postpartum Depression and Body Image Dissatisfaction, Self-objectification, and Social Media Appearance Comparison |
NOT_YET_RECRUITING | |
| NCT07523932 |
Midwife-Led Digital Follow-Up After Cesarean Section |
NOT_YET_RECRUITING | NA |
| NCT07515222 |
Efficacy of Yoga-Based Intervention in Improving Mother-Child Bonding in Maternal Depression |
NOT_YET_RECRUITING | NA |
| NCT07506759 |
The Effect of Psychodramatic Role-Playing on Postpartum Depression, Self-Efficacy, and Perceived Social Support |
COMPLETED | NA |
| NCT07398469 |
A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone |
RECRUITING | |
| NCT07354334 |
Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outcomes |
ENROLLING_BY_INVITATION | NA |
| NCT07312812 |
The Effect of Art-Based Mandala Coloring Activity on Postpartum Anxiety and Postpartum Depression |
NOT_YET_RECRUITING | NA |
| NCT07267702 |
Postpartum 1-Day CBT Pilot Study (Türkiye) |
NOT_YET_RECRUITING | NA |
| NCT07167654 |
Smartphone Application to Support Mothers at Risk of Postpartum Depression |
ACTIVE_NOT_RECRUITING | NA |
| NCT07083492 |
Non-invasive Detection of Iron Deficiency in Obstetrics |
RECRUITING |
