Also known as: gum disease
A review of more than 200 studies linked up to a third of dementia cases to diseases outside the brain. Trials and broader evidence also support multi-domain prevention strategies.
Medivir's 2025 Annual Report highlights FDA Orphan Drug Designation for MIV-711 in Osteogenesis Imperfecta and promising fostrox liver cancer data showing 13.7-month median survival. The company raised SEK 196 million to fund Phase 2 studies for both programs and reported year-end cash of SEK 119.2 million.
Researchers at Texas A&M University have developed a tissue-adhesive biosensor that detects inflammation biomarkers in the mouth with molecular precision, potentially shifting oral healthcare from reactive to proactive.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07770906 |
Effect of GLP-1 Receptor Agonists on Periodontal Health and Response to Nonsurgical Periodontal Therapy |
NOT_YET_RECRUITING | NA |
| NCT07759466 |
Hippo Signaling Pathway Proteins in Gingival Crevicular Fluid of Individuals With Periodontal Disease |
COMPLETED | |
| NCT07745803 |
Discovery and Validation of Biomarkers for Periodontitis, Dental Caries and Oral Squamous Cell Carcinoma |
NOT_YET_RECRUITING | |
| NCT07737678 |
Evaluation of NIPSA Using Alloplastic Bone Graft and Cross-Linked Hyaluronic Acid in theTreatment of Intrabony Defects |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07731113 |
Evaluation of Hyaluronic Acid and Chlorhexidine Gel as an Adjunct to Minimally Invasive Non-surgical Therapy in the Treatment of Stage III and IV Periodontitis |
ACTIVE_NOT_RECRUITING | NA |
| NCT07725913 |
Thermosensitive Hyaluronic Gel With Octenidine as an Adjunctive to Subgingival Instrumentation. Spontaneous, Postmarketing Trial With a Medical Device (MD), Split-mouth, Nationwide Multicenter Study Single-blind Randomized Controlled Trial |
RECRUITING | NA |
| NCT07725276 |
Comparing the Efficacy of Toothbrushing With and Without Interproximal Cleaning Aids: A Split-Mouth Trial |
COMPLETED | NA |
| NCT07721428 |
Salivary Angiotensin-Converting Enzyme and Periodontal Disease in Cardiovascular Disease |
COMPLETED | |
| NCT07718074 |
Probiotic Response in Periodontal Disease |
NOT_YET_RECRUITING | NA |
| NCT07711431 |
Association Between Periodontal Disease and Chronic Neck Pain |
RECRUITING |
