A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibition
- Status
- ACTIVE_NOT_RECRUITING
- Phase
- PHASE3
Clinical Trials Related to Paroxysmal Nocturnal Hemoglobinuria
Related studies linked through entity extraction aliases.
Danicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)
- Status
- COMPLETED
- Phase
- PHASE3
Efficacy and Safety of Elizaria® vs. Soliris® in Patients With PNH
- Status
- COMPLETED
- Phase
- PHASE3
A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors
- Status
- ACTIVE_NOT_RECRUITING
- Phase
- PHASE3
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors
- Status
- ACTIVE_NOT_RECRUITING
- Phase
- PHASE3
First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH
- Status
- COMPLETED
- Phase
- PHASE1/PHASE2
Ravulizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Currently Treated With High-Dose Eculizumab
- Status
- COMPLETED
- Phase
- PHASE4
REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate Its Long Term Safety, Efficacy and Tolerability.
- Status
- TERMINATED
- Phase
- PHASE3
Electronic Patient-reported Outcome Monitoring in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria
- Status
- COMPLETED
- Phase
- N/A
A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With PNH
- Status
- COMPLETED
- Phase
- PHASE3
The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria
- Status
- COMPLETED
- Phase
- N/A
Clinical Trial of BCD-148 and Soliris® for the Treatment of Patients With Paroxysmal Nocturnal Hemoglobinuria
- Status
- COMPLETED
- Phase
- PHASE3
A Study to Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria
- Status
- COMPLETED
- Phase
- PHASE3
Efficacy, Safety, Pharmacokinetics and Pharmacodynamics Study, Assessing Multiple LNP023 Doses in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria
- Status
- COMPLETED
- Phase
- PHASE2
Sirolimus Combined With Low-dose Warfarin for the Treatment of Refractory PNH
- Status
- UNKNOWN
- Phase
- PHASE4
rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study
- Status
- TERMINATED
- Phase
- PHASE3
A Study Evaluating the Efficacy and Safety of ABP 959 Compared With Eculizumab in Adult Participants With PNH
- Status
- COMPLETED
- Phase
- PHASE3
Ravulizumab Subcutaneous (SC) Versus Ravulizumab Intravenous (IV) in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab
- Status
- COMPLETED
- Phase
- PHASE3
Study to Evaluate the Efficacy and Safety of APL-2 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Status
- COMPLETED
- Phase
- PHASE3
A Study of Ravulizumab (ALXN1210) in Children and Adolescents With Paroxysmal Nocturnal Hemoglobinuria
- Status
- COMPLETED
- Phase
- PHASE3