AI Tools and Partnerships Advance Precision Medicine
Yale researchers built genomic AI models for personalized medicine. The University of Liverpool and BPGbio will expand AI drug discovery via the NAi platform.
Mitochondrial Disease
DiseaseRelated News
Red Blood Cells Act as Glucose Sponges at High Altitude, Lowering Diabetes Risk
New research reveals red blood cells absorb large amounts of glucose in low-oxygen conditions, explaining why high-altitude populations have lower diabetes rates. A drug mimicking this effect completely reversed high blood sugar in diabetic mice.
High Altitude Protects Against Diabetes by Turning Red Blood Cells Into Glucose Sponges
Scientists at Gladstone Institutes have discovered why living at high altitude reduces diabetes risk: red blood cells absorb large amounts of glucose in low oxygen environments. A drug mimicking this effect reversed diabetes in mice.
Related Clinical Trials
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07511608 |
Development of a New Technique for Quantifying Mitochondrial DNA in Single Muscle Fibers |
NOT_YET_RECRUITING | NA |
| NCT07258667 |
Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy |
NOT_YET_RECRUITING | PHASE1 |
| NCT07159139 |
Vatiquinone Expanded Access Protocol |
NO_LONGER_AVAILABLE | |
| NCT06931834 |
Expanded Access Program for R007 (Probucol) Tablets in Adults With Mitochondrial Disease and Chronic Kidney Disease |
AVAILABLE | |
| NCT06819683 |
Validation of Nanosensor Oxygen Measurement |
RECRUITING | PHASE1 |
| NCT05241262 |
Study of N-acetylcysteine in the Treatment of Patients With the m.3243A>G Mutation and Low Brain Glutathione Levels |
RECRUITING | PHASE1 |
| NCT04643249 |
Drug-drug Interaction Study of KL1333 in Healthy Subjects |
COMPLETED | PHASE1 |
| NCT04419870 |
Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity |
RECRUITING | |
| NCT02985710 |
Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan |
COMPLETED | NA |
| NCT02745938 |
GDF-15 as a Biomarker for Mitochondrial Disease |
COMPLETED |