Vatiquinone Expanded Access Protocol

Safety Study of Fenretinide in Adult Patients With Cystic Fibrosis

NCT02141958 ·Status: COMPLETED ·Phase: PHASE1

Clinical Outcomes of Triple Combination Therapy in Severe Cystic Fibrosis Disease.

NCT04038710 ·Status: COMPLETED

Interest of Gentamicin-induced Readthrough in Cystic Fibrosis Patients

NCT00376428 ·Status: TERMINATED ·Phase: PHASE2

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

NCT02070744 ·Status: COMPLETED ·Phase: PHASE2

Study of VX-809 in Cystic Fibrosis Subjects With the ∆F508-CFTR Gene Mutation

NCT00865904 ·Status: COMPLETED ·Phase: PHASE2

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

NCT01531673 ·Status: COMPLETED ·Phase: PHASE2

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older With the G551D Mutation

NCT00909532 ·Status: COMPLETED ·Phase: PHASE3

A Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation

NCT02516410 ·Status: COMPLETED ·Phase: PHASE3

Assessment of Quadriceps Muscle Electrostimulation Used in Patients Suffering From Cystic Fibrosis

NCT00391703 ·Status: TERMINATED ·Phase: NA

A Phase 3 Study to Evaluate the Efficacy and Safety of Ivacaftor and VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutation

NCT02392234 ·Status: COMPLETED ·Phase: PHASE3

Study to Evaluate the Safety and Efficacy of CTP-656 in Patients With Cystic Fibrosis With CFTR Gating Mutations

NCT02971839 ·Status: TERMINATED ·Phase: PHASE2

A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation

NCT02709109 ·Status: COMPLETED ·Phase: PHASE2

PTC124 for Cystic Fibrosis

NCT00234663 ·Status: COMPLETED ·Phase: PHASE2

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

NCT03912233 ·Status: COMPLETED ·Phase: PHASE2

Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis

NCT03768089 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Validation of Therapeutic Efficacy Targeting the Splicing Variants in Cystic Fibrosis and CFTR Pathologies

NCT05100823 ·Status: TERMINATED ·Phase: NA

Phase I Pilot Study of Ad5-CB-CFTR, an Adenovirus Vector Containing the Cystic Fibrosis Transmembrane Conductance Regulator Gene, in Patients With Cystic Fibrosis

NCT00004779 ·Status: COMPLETED ·Phase: PHASE1

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

NCT05444257 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

A Study of VX-445 in Healthy Subjects and Subjects With Cystic Fibrosis

NCT03227471 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients

NCT02190604 ·Status: TERMINATED ·Phase: PHASE1/PHASE2

PTC124 for the Treatment of Cystic Fibrosis

NCT00351078 ·Status: COMPLETED ·Phase: PHASE2

Volatilomic Approaches for the Study of CFTR Modulators (VOLATIL-CF)

NCT05726994 ·Status: UNKNOWN

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor

NCT02347657 ·Status: COMPLETED ·Phase: PHASE3

Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have a Non-G551D CF Transmembrane Conductance Regulator (CFTR) Gating Mutation

NCT01614470 ·Status: COMPLETED ·Phase: PHASE3

Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have the R117H-CF Transmembrane Conductance Regulator (CFTR) Mutation (KONDUCT)

NCT01614457 ·Status: COMPLETED ·Phase: PHASE3