Generalized anxiety disorder is characterized by excessive, difficult-to-control worry across multiple domains accompanied by physical and cognitive symptoms that cause significant distress or impairment.
Helus Pharma announced publication in Nature Medicine of Phase 2a trial results showing its short-acting psychedelic SPL026 met its primary endpoint with significant reductions in depressive symptoms at two weeks in moderate-to-severe MDD patients. The company also appointed a new SVP of Medical Affairs and is advancing HLP003 (Breakthrough Therapy Designation from FDA) and HLP004 in its pipeline.
Compass Pathways reported positive late-stage COMP360 psilocybin data in treatment-resistant depression and plans FDA talks ahead of a filing between October and December. The update lifted shares across several psychedelics developers.
New clinical trials show single doses of psilocybin and LSD produce significant, lasting reductions in OCD and generalized anxiety disorder symptoms for up to 12 weeks, marking a potential shift from daily medication regimens.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07579897 |
Group vs. Individual Metacognitive Therapy for Generalized Anxiety Disorder |
RECRUITING | NA |
| NCT07577271 |
THE EFFECT OF YOGA-ASSISTED COGNITIVE BEHAVIORAL THERAPY ON INDIVIDUALS DIAGNOSED WITH GENERALIZED ANXIETY DISORDER |
NOT_YET_RECRUITING | NA |
| NCT07489651 |
RE104 Safety and Efficacy Study in Generalized Anxiety Disorder |
RECRUITING | PHASE2 |
| NCT07028216 |
Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method |
RECRUITING | NA |
| NCT06934525 |
Implementing Team-Based Treatment for Pediatric Anxiety in Community Mental Health Settings |
RECRUITING | NA |
| NCT06809595 |
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama) |
ACTIVE_NOT_RECRUITING | PHASE3 |
| NCT06741228 |
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage) |
ACTIVE_NOT_RECRUITING | PHASE3 |
| NCT05800925 |
Triage Survey for Psychiatry Research Eligibility |
RECRUITING | |
| NCT04793828 |
A Transdiagnostic, Self-guided Internet Intervention ("Velibra") for Waitlist Patients With Anxiety Disorders |
RECRUITING | NA |
| NCT03585010 |
Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders |
COMPLETED | NA |
