News Related to Fallopian Tube Cancer

FDA Grants Fast Track to SIM0505 for Platinum-Resistant Ovarian Cancer

Apr 08, 2026

The FDA granted fast track designation to SIM0505, a CDH6-targeting antibody-drug conjugate, for platinum-resistant ovarian cancer based on preclinical and early clinical data. A phase 1 trial is currently evaluating the drug in advanced solid tumors, with initial data expected at the 2026 ASCO conference. The company plans to begin dose optimization studies in ovarian cancer patients in Q2 2026.

Alphamab Oncology Doses First Patient in Phase III Trial of JSKN003 for HER2-Positive CRC

Feb 15, 2026

Alphamab Oncology dosed the first patient in its Phase III trial of JSKN003, a biparatopic HER2-targeting antibody-drug conjugate, for HER2-positive advanced colorectal cancer on February 14, 2026.

Alphamab Oncology Doses First Patient in Phase III Trial of JSKN003 for Colorectal Cancer

Feb 14, 2026

Alphamab Oncology has dosed the first patient in a Phase III study of JSKN003, a biparatopic HER2-targeting ADC, for HER2-positive advanced colorectal cancer. The drug demonstrated a 68.8% response rate in earlier trials.