News Related to Depression

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Genetic Framework Identifies Depression Drug Targets and Repurposing Opportunities

Jun 15, 2026

A genetic framework using Mendelian randomization identified and prioritized drug targets for major depression from over 525,000 cases. The study found drugs targeting genetically supported proteins are 2.6 times more likely to succeed and prioritized 54 repurposing opportunities using existing medications for other conditions.

Vaccine Denial Risks Increasing Chronic Illness, Historical Patterns Show

Jun 11, 2026

Vaccine denial and weakened public health measures risk increasing chronic illness, as historical data shows post-infectious conditions follow major outbreaks. Long COVID affects 10-20% of those infected, while historical pandemics led to conditions like encephalitis lethargica with near 50% mortality.

Study Links Teen Cannabis Use to Higher Risk of Mental Health Disorders

Apr 07, 2026

A large Kaiser Permanente study of 463,396 adolescents found those using cannabis were twice as likely to develop psychotic or bipolar disorders, with elevated risks for depression and anxiety. The research suggests adolescence is a vulnerable period for cannabis-related mental health harms, though causality remains complex.

NRx says FDA outlined path for NRX-100 depression drug application

Apr 06, 2026

NRx said the FDA outlined a path for a New Drug Application for NRX-100, a preservative-free ketamine formulation for depression with suicidality. The company plans to submit the NDA by June 2026 and said no additional nonclinical or bridging studies would be required.