Birth defects are structural or functional conditions that are present at birth and can affect almost any part of the body. They can vary from mild to severe and may be caused by genetic, environmental, or unknown factors.
New research challenges the theory that ketamine's psychedelic effects drive its therapeutic benefits for alcohol use disorder. A study of 96 participants found no link between ketamine's psychoactive experiences and improved abstinence rates. The findings suggest other mechanisms, such as brain network alterations, may explain ketamine's effectiveness in treating addiction.
Researchers at Monash University have identified DNA sequence variations in mothers that modify the risk of birth defects from valproic acid, an anti-seizure medication, paving the way for a genetic test to identify who can safely take the drug during pregnancy.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07514377 |
JiGenerations Health Cohort Study：Parental Exposure and Intergenerational Health in China |
ACTIVE_NOT_RECRUITING | |
| NCT06048276 |
Miscarriage Preventing Herbal Medicines and the Risk of Birth Defects: a Population-based Cohort Study |
ACTIVE_NOT_RECRUITING | |
| NCT05318222 |
Genetic Inclusion by Virtual Evaluation |
RECRUITING | NA |
| NCT04182503 |
Environmental Factors and Embryonic Development Project |
UNKNOWN | |
| NCT03725878 |
Effectiveness of Comprehensive Tertiary Interventions on Incidence and Clinical Outcomes of Birth Defects |
COMPLETED | NA |
| NCT03215368 |
The Ma'Anshan Birth Cohort (MABC) |
ACTIVE_NOT_RECRUITING | |
| NCT02391610 |
The China-Anhui Birth Cohort Study (C-ABCS) |
COMPLETED | |
| NCT02055248 |
Study on Moebius Syndrome and Congenital Facial Weakness Disorders |
COMPLETED | |
| NCT01294345 |
Personalized Genomic Research |
COMPLETED | |
| NCT01097720 |
Developmental Delay in Children Exposed During Pregnancy to Either Lamotrigine,Sodium Valproate, or Carbamazepine |
UNKNOWN |
