The FDA fast-tracked an inhalable gene therapy for advanced lung cancer after an early 11-patient trial showed tumour shrinkage in three patients and disease stabilization in five. Larger studies involving about 250 patients are underway.
Moderna and Merck are recruiting patients for a Phase 2 trial testing V940, an mRNA-based cancer vaccine, combined with Keytruda and chemotherapy as first-line treatment for metastatic squamous non-small cell lung cancer.
Moderna and Merck have begun recruiting for a Phase 2 trial testing V940, an mRNA-based personalized cancer vaccine, combined with Keytruda and chemotherapy as first-line treatment for metastatic squamous non-small cell lung cancer.
A randomized trial of 210 advanced lung cancer patients found that administering checkpoint inhibitor immunotherapy in the morning nearly doubled progression-free survival and extended overall survival by nearly a year compared to later-day dosing.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07726212 |
A First-in-human (FIH), Open-Label, Dose Escalation and Expansion Cohorts Study of MC002 |
NOT_YET_RECRUITING | PHASE1 |
| NCT07708870 |
Nurse-Led Caregiver Support for Older Adults With Advanced Lung Cancer |
RECRUITING | NA |
| NCT07689968 |
A Pilot Study of the VosCryoTM Breathalyser in Lung Cancer |
NOT_YET_RECRUITING | |
| NCT07673419 |
A Clinical Study GK01 Cell Injection in Subjects With Advanced Lung Cancer |
NOT_YET_RECRUITING | EARLY_PHASE1 |
| NCT07498972 |
Evidence-Based Nursing Plus Progressive Exercise for Cancer-Related Fatigue in Advanced Lung Cancer |
COMPLETED | NA |
| NCT07490639 |
Family-Supported Palliative Care in Advanced Lung Cancer |
COMPLETED | NA |
| NCT07405931 |
Evaluation of the Effectiveness of Managing Chemotherapy Side Effects Using ePRO and a Standardized Telenursing Program for Cancer Patients |
RECRUITING | NA |
| NCT07391956 |
Tier Palliative Care For Patients With Advanced Heart Failure or Cancer |
NOT_YET_RECRUITING | NA |
| NCT07367529 |
A Clinical Trial on the Efficacy and Safety of TQB6411 for Injection |
RECRUITING | PHASE1/PHASE2 |
| NCT07309276 |
A Phase II Clinical Study Evaluating the Combination Therapy of JS212 in Patients With Advanced Lung Cancer |
RECRUITING | PHASE2 |
