Also known as: Wellcome
Two studies reveal how 3D genome architecture shapes early human development. One shows enhancers pre-connect with future target genes before activation, while the other finds germ cells restructure chromosomes before meiosis — a step critical for lab-grown sperm and eggs.
Advances in precision mental health research include TMS findings published in Nature Molecular Psychiatry showing targeted brain stimulation can address specific depression and anxiety symptoms, the launch of the three-year GlobalMinds NHS genomic study analyzing 49,000 DNA samples, and the new $1 million Wellcome Prize for Mental Health Science.
Scientists at UCL have discovered that the protein LRG1 triggers the earliest damage in diabetic retinopathy by constricting retinal blood vessels. Blocking LRG1 in diabetic mice prevented early retinal damage and preserved normal eye function.
Juvenescence, a clinical-stage AI-enabled biotech company, has appointed Eileen Jennings-Brown as Chief Technology Officer and established new research offices at Masdar City in Abu Dhabi to advance its longevity therapeutics pipeline.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07758972 |
Safety and Immunogenicity Study of a Multivalent Gonorrhoea Vaccine |
RECRUITING | PHASE1 |
| NCT07694076 |
Repeated Real-time Biofeedback With 7-Tesla MRI for Treatment of Depression |
RECRUITING | NA |
| NCT07167316 |
The Role of the LC-NA System in Experimental Sleep Fragmentation |
RECRUITING | PHASE1 |
| NCT07085702 |
A Study to Evaluate Safety, Reactogenicity, and Immunogenicity of the GSK 4-component Strep A Vaccine With Aluminum Hydroxide (Alum) or AS37 in Healthy Young Adults |
RECRUITING | PHASE1 |
| NCT07082465 |
Epidemiology of Antimicrobial-use and Antimicrobial-resistant Infections in Four Hospitals in Thailand |
ACTIVE_NOT_RECRUITING | |
| NCT07035769 |
A First-in-Human Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Multiple Oral Doses of Debio 1453P in Healthy Adults |
RECRUITING | PHASE1 |
| NCT06719219 |
A First in Human Trial to Assess the Safety and Immunogenicity of LTB-SA7 Vaccine Against Staphylococcus Aureus. |
COMPLETED | PHASE1 |
| NCT06188754 |
Healthy Lifestyles for Bipolar Disorder |
RECRUITING | NA |
| NCT05859412 |
Mechanisms of Neurodynamic Treatments |
COMPLETED | NA |
| NCT05784701 |
Trivalent Salmonella Conjugate Vaccine (TSCV) |
ACTIVE_NOT_RECRUITING | PHASE2 |
