Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype
- Status
- COMPLETED
- Phase
- PHASE2
Clinical Trials Related to Vertex Pharmaceuticals Incorporated
Related studies linked through entity extraction aliases.
A Study Evaluating the Long-Term Safety of Elexacaftor Combination Therapy
- Status
- COMPLETED
- Phase
- PHASE3
A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes
- Status
- COMPLETED
- Phase
- PHASE3
Phase 2a Study of VX-147 in Adults With APOL1-mediated Focal Segmental Glomerulosclerosis
- Status
- COMPLETED
- Phase
- PHASE2
Organoid Study R334W
- Status
- WITHDRAWN
- Phase
- NA
Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation
- Status
- COMPLETED
- Phase
- PHASE3
A Long-term Follow-up Study in Participants Who Received CTX001
- Status
- ENROLLING_BY_INVITATION
- Phase
- PHASE3
Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA TC Combination Therapy in Participants With Cystic Fibrosis Who Are 6 Years of Age and Older
- Status
- COMPLETED
- Phase
- PHASE3
Evaluation of the Efficacy and Safety of VX-814 in Subjects With the PiZZ Genotype
- Status
- TERMINATED
- Phase
- PHASE2
Effect of Lumacaftor/Ivacaftor in Children With Cystic Fibrosis Homozygote for F508del on Small Airway Function
- Status
- COMPLETED
- Phase
- N/A
A Study Evaluating the Efficacy and Safety of VX-445/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects, Homozygous for F508del
- Status
- COMPLETED
- Phase
- PHASE3
The Multicenter Topic Trial
- Status
- WITHDRAWN
- Phase
- PHASE2
Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy
- Status
- COMPLETED
- Phase
- PHASE3
A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)
- Status
- COMPLETED
- Phase
- PHASE3
VX-445/TEZ/IVA Expanded Access Program for Cystic Fibrosis (CF) Patients Heterozygous for F508del Mutation and a Minimal Function Mutation (F/MF Genotypes)
- Status
- APPROVED_FOR_MARKETING
- Phase
- N/A
A Study Evaluating the Long-term Safety of VX-445 Combination Therapy
- Status
- COMPLETED
- Phase
- PHASE3
Gut Imaging for Function & Transit in Cystic Fibrosis Study 2
- Status
- COMPLETED
- Phase
- PHASE2
A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis
- Status
- COMPLETED
- Phase
- PHASE2
A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis
- Status
- COMPLETED
- Phase
- PHASE2
Gastrointestinal Study at Orkambi Therapy in CF Patients
- Status
- UNKNOWN
- Phase
- N/A