Young Onset Parkinson's Disease Subtypes and Pathogenic Mechanisms

NCT07752355 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2026-08-12

No results posted yet for this study

Summary

Young Onset Parkinson's disease (YOPD) refers to a group of patients in which the disease starts earlier in life (before the age of 50 years) and has a profound impact on most of patient's life. Current knowledge regarding the mechanisms leading to development of Parkinson's disease in younger individuals is lacking, but their understanding is crucial for the successful design of therapeutic strategies and stratifying patients for clinical trials. With this research the investigators aim to clarify the contribution of relevant biological processes in patients with Young onset Parkinson's disease to help understanding disease mechanisms and biomarkers.

Conditions

  • Young Onset Parkinson Disease
  • Parkinson Disease

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    collaborator NIH
  • NYU Langone Health

    lead OTHER

Principal Investigators

  • Giulietta Riboldi, MD, PhD · NYU Langone Health

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-02-28
Primary Completion
2028-10-31
Completion
2028-10-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07752355 on ClinicalTrials.gov