A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy
- Status
- RECRUITING
- Phase
- PHASE2
Clinical Trials Related to Alnylam Pharmaceuticals
Related studies linked through entity extraction aliases.
Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy
- Status
- ACTIVE_NOT_RECRUITING
- Phase
- N/A
Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)
- Status
- COMPLETED
- Phase
- PHASE2
Lumasiran in Hyperoxalaemic Patients on Haemodialysis
- Status
- RECRUITING
- Phase
- PHASE2
RWE-based Treatment Patterns and Outcomes in CIDP
- Status
- UNKNOWN
- Phase
- N/A
A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM
- Status
- TERMINATED
- Phase
- PHASE1/PHASE2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALN-TTRSC04 in Healthy Subjects
- Status
- COMPLETED
- Phase
- PHASE1
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF
- Status
- RECRUITING
- Phase
- NA
Expanded Access Protocol to Provide Patisiran to Patients With Transthyretin-mediated Amyloidosis With Cardiomyopathy
- Status
- NO_LONGER_AVAILABLE
- Phase
- N/A
A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout
- Status
- TERMINATED
- Phase
- PHASE1/PHASE2
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
- Status
- RECRUITING
- Phase
- PHASE1
A Study to Evaluate Lumasiran in Adults With Recurrent Calcium Oxalate Kidney Stone Disease and Elevated Urinary Oxalate Levels
- Status
- TERMINATED
- Phase
- PHASE2
Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)
- Status
- COMPLETED
- Phase
- PHASE2
Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program
- Status
- RECRUITING
- Phase
- N/A
Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy
- Status
- COMPLETED
- Phase
- EARLY_PHASE1
BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)
- Status
- ACTIVE_NOT_RECRUITING
- Phase
- N/A
A Study to Evaluate Efficacy and Safety of ALN-AGT01 in Patients With Mild To-Moderate Hypertension
- Status
- COMPLETED
- Phase
- PHASE2
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)
- Status
- RECRUITING
- Phase
- N/A
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Pozelimab in Combination With Cemdisiran in Healthy Adult Volunteers
- Status
- COMPLETED
- Phase
- PHASE1
A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH)
- Status
- TERMINATED
- Phase
- PHASE1