ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP)
- Status
- COMPLETED
- Phase
- PHASE3
Clinical Trials Related to Alnylam Pharmaceuticals
Related studies linked through entity extraction aliases.
A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome
- Status
- WITHDRAWN
- Phase
- PHASE2
TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects
- Status
- COMPLETED
- Phase
- N/A
A Study to Evaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP)
- Status
- COMPLETED
- Phase
- PHASE1/PHASE2
Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)
- Status
- APPROVED_FOR_MARKETING
- Phase
- N/A
A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection
- Status
- TERMINATED
- Phase
- PHASE1
A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy Subjects
- Status
- COMPLETED
- Phase
- PHASE1
Study of Lumasiran in Healthy Adults and Patients With Primary Hyperoxaluria Type 1
- Status
- COMPLETED
- Phase
- PHASE1/PHASE2
The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant
- Status
- COMPLETED
- Phase
- PHASE2
The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Participants Who Have Already Been Treated With ALN-TTR02 (Patisiran)
- Status
- COMPLETED
- Phase
- PHASE3
A Study of an Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease
- Status
- TERMINATED
- Phase
- PHASE1
A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)
- Status
- COMPLETED
- Phase
- PHASE1
A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH
- Status
- COMPLETED
- Phase
- PHASE1/PHASE2
ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)
- Status
- COMPLETED
- Phase
- PHASE3
A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)
- Status
- COMPLETED
- Phase
- PHASE1
A Extension Study to Evaluate Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Cardiac Amyloidosis
- Status
- COMPLETED
- Phase
- PHASE2
DISCOVERY: A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis
- Status
- COMPLETED
- Phase
- N/A
EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)
- Status
- COMPLETED
- Phase
- N/A
A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers
- Status
- COMPLETED
- Phase
- PHASE1
Phase 2 Study to Evaluate ALN-TTRSC (Revusiran) in Patients With Transthyretin (TTR) Cardiac Amyloidosis
- Status
- COMPLETED
- Phase
- PHASE2