Clinical Trials Updated in April 2022

NCT05354843 | UNKNOWN | PHASE1

37 participants

SHP2 Inhibitor ET0038 Monotherapy in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-10-27
Completion:: 2023-10-01

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT05354817 | UNKNOWN | PHASE2

25 participants

Impact of FOLFIRINOX Chemotherapy in IV Stage Colorectal Cancer Patients Previously Exposed to Irinotecan, Fluoropyrimidine and Oxaliplatin

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-10-22
Completion:: 2022-12-31

Conditions

Colorectal Cancer Stage IV

Interventions

DRUG

No Results Yet

NCT05354739 | COMPLETED

300 participants

Comparing Buzzy Device With Emla Cream in Needle Related Pain

Study Type:: OBSERVATIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-02-02
Completion:: 2021-09-29

Conditions

Procedural Pain

Interventions

DEVICE

No Results Yet

NCT05354635 | UNKNOWN

280 participants

Therapeutic Follow-up of Antibiotics in Pediatric Intensive Care

Study Type:: OBSERVATIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-06-30
Completion:: 2025-06-30

Conditions

Intensive Care Units, Pediatric

Interventions

OTHER

No Results Yet

NCT05354518 | UNKNOWN | NA

78 participants

Teaching Method With Simulation in Gestational Diabetes Mellitus Management

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-04-19
Completion:: 2022-04-19

Conditions

Diabetes, Gestational

Interventions

BEHAVIORAL

No Results Yet

NCT05354492 | UNKNOWN | NA

400 participants

Evaluating a New Program for Successfully Coping With Adversity

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-02-01
Completion:: 2022-07-31

Conditions

Trauma
Distress, Emotional
Psychological Distress

Interventions

OTHER

No Results Yet

NCT05354479 | UNKNOWN | PHASE4

60 participants

Breastmilk Alone or in Combination With Paracetamol for Reducing Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-10-20
Completion:: 2022-04-19

Conditions

Pain Control

Interventions

DRUG

No Results Yet

NCT05354388 | UNKNOWN

30 participants

Ripretinib Combined With Surgery in Advanced GIST That Have Failed Imatinib Therapy: A Multicenter,Observational Study

Study Type:: OBSERVATIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-10-01
Completion:: 2023-12-30

Conditions

Gastrointestinal Stromal Tumor(GIST)

Interventions

PROCEDURE

No Results Yet

NCT05354375 | RECRUITING | PHASE1

20 participants

Clinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-12-01
Completion:: 2025-11-30

Conditions

Immunotherapy

Interventions

BIOLOGICAL

No Results Yet

NCT05354310 | UNKNOWN | NA

220 participants

The VOILA Intervention Study

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-02-01
Completion:: 2024-02-01

Conditions

Aging

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05354284 | ACTIVE_NOT_RECRUITING

200 participants

Physical and Mental Health Among Sexual and Gender Minorities During Pregnancy, Birth and Postpartum

Study Type:: OBSERVATIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-10-01
Completion:: 2026-12-31

Conditions

Sexual and Gender Minorities
Pregnancy Complications
Obstetric Complication
Psychological Trauma

Interventions

OTHER

No Results Yet

NCT05354271 | UNKNOWN | NA

150 participants

High-intensity Interval Training in Patients With Atrial Fibrillation

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-08-27
Completion:: 2023-01-27

Conditions

Atrial Fibrillation

Interventions

OTHER

No Results Yet

NCT05354154 | UNKNOWN

249 participants

Incidence of Postoperative Sore-throat Incidence

Study Type:: OBSERVATIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-04-01
Completion:: 2023-01-31

Conditions

Sore-throat

Interventions

PROCEDURE

No Results Yet

NCT05354076 | UNKNOWN | PHASE2

30 participants

Study on the Correlation Between Immunoglobulin and Liposomal Doxorubicin in Vivo

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2000-03-01
Completion:: 2022-06-01

Conditions

Advanced Malignant Tumors

Interventions

DRUG

No Results Yet

NCT05354050 | COMPLETED | PHASE1

21 participants

Pharmacokinetic Study of DARE-BV1

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2020-11-03
Completion:: 2020-11-18

Conditions

Bacterial Vaginosis

Interventions

DRUG

No Results Yet

NCT05354037 | UNKNOWN | NA

40 participants

Flapless Approach for the Treatment of Intrabony Defects

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-05-13
Completion:: 2022-12-30

Conditions

Intrabony Periodontal Defect

Interventions

PROCEDURE

No Results Yet

NCT05354011 | UNKNOWN | NA

38 participants

Effects of Kinesiotaping With and Without Active Release Technique in Patients With Carpal Tunnel Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-04-15
Completion:: 2022-08-15

Conditions

Carpal Tunnel Syndrome

Interventions

OTHER

No Results Yet

NCT05353946 | RECRUITING | NA

124 participants

Coronary Rotational Atherectomy Elective vs. Bailout in Severely Calcified Lesions and Chronic Renal Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2019-02-02
Completion:: 2022-12-27

Conditions

Coronary Artery Disease
Chronic Renal Failure

Interventions

DEVICE

No Results Yet

NCT05353907 | NOT_YET_RECRUITING

78 participants

Dual-Energy Computed Tomography for Improving Imaging Assessment of Multiple Myeloma

Study Type:: OBSERVATIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-06-30
Completion:: 2025-12-31

Conditions

Myeloma

Interventions

RADIATION

No Results Yet

NCT05353894 | UNKNOWN | PHASE1

27 participants

Effect of Food and Formulation on the Pharmacokinetics, Safety, and Tolerability of GNS561 After One Single Dose (50 and 200mg) in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-05-02
Completion:: 2022-11-30

Conditions

Primary Liver Cancer

Interventions

DRUG

No Results Yet

NCT05353712 | UNKNOWN | NA

20 participants

Effect of Consuming Products Containing Rare Sugars Alongside Sucrose on Glycaemic Response in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-05-31
Completion:: 2022-11-30

Conditions

Glycaemic Response in Healthy Participants

Interventions

OTHER

No Results Yet

NCT05353699 | UNKNOWN | NA

12648 participants

Implementation of a Comprehensive Intervention on Hypertension（HTN） and Type 2 Diabetes Mellitus（DM） at PHC Level

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-05-01
Completion:: 2023-01-31

Conditions

Hypertension
Diabetes Mellitus, Type 2

Interventions

OTHER

No Results Yet

NCT05353686 | COMPLETED | PHASE2

54 participants

A Trial Investigating the Effect of 4 Weeks Dosing of XEN-D0501 on Blood Glucose Reduction in Patients With Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2019-02-25
Completion:: 2019-12-19

Conditions

Efficacy
Safety
Pharmacokinetics
Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT05353673 | UNKNOWN | PHASE2

120 participants

The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-06-01
Completion:: 2022-12-01

Conditions

Immune Thrombocytopenia
Blood Coagulation Disorders
Thrombocytopenia
Physiological Effects of Drugs

Interventions

DRUG

No Results Yet

NCT05353634 | COMPLETED

2022097 participants

Metagenomic Sequencing in Clinical Infectious Diseases

Study Type:: OBSERVATIONAL
Last Updated:: 2022-04-29
Start Date:: 2020-06-10
Completion:: 2021-10-16

Conditions

Bacterial Infections and Mycoses

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05353582 | UNKNOWN | PHASE2

168 participants

Preoperative Systemic Therapy for Colorectal Cancer Peritoneal Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-06-01
Completion:: 2025-07-01

Conditions

Colorectal Neoplasms
Colorectal Cancer
Colorectal Cancer Metastatic
Peritoneal Metastases
Peritoneal Cancer
Peritoneal Neoplasms
Chemotherapy Effect
Cytoreductive Surgery
Hyperthermic Intraperitoneal Chemotherapy

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05353543 | NOT_YET_RECRUITING | NA

120 participants

Acupuncture Therapy Based on Biological Specificity of Acupoints for Major Depressive Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-05-01
Completion:: 2025-05-30

Conditions

Major Depressive Disorder

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05353504 | RECRUITING | NA

90 participants

Impact of Microbiome-changing Interventions on Food Decision-making

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-03-08
Completion:: 2024-12-31

Conditions

Overweight and Obesity

Interventions

DIETARY_SUPPLEMENT
BEHAVIORAL

No Results Yet

NCT05353426 | COMPLETED | NA

145 participants

Paragastric Autonomic Blockade to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-08-13
Completion:: 2022-02-03

Conditions

Visceral Pain
Bariatric Surgery Candidate
Pain, Postoperative
Vomiting, Postoperative
Nausea, Postoperative

Interventions

PROCEDURE

No Results Yet

NCT05353413 | UNKNOWN | NA

20 participants

Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2020-01-01
Completion:: 2024-01-01

Conditions

Ischemic Optic Neuropathy
Optic Neuritis
Compressive Optic Neuropathy
Traumatic Optic Neuropathy
Toxic Optic Neuropathy
Hereditary Optic Neuropathies

Interventions

DEVICE
DIAGNOSTIC_TEST

No Results Yet

NCT05353309 | UNKNOWN | NA

350 participants

Iliac Angioplasties: Impact of the Fusion of Images on the Irradiation Rate

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-05-25
Completion:: 2023-09-30

Conditions

Irradiation Rate
Image, Body
Iliac Artery Disease

Interventions

PROCEDURE

No Results Yet

NCT05353205 | UNKNOWN | PHASE4

200 participants

A Study of the Efficacy and Safety of Flumatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase.

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2021-11-23
Completion:: 2022-12-30

Conditions

CML, Chronic Phase

Interventions

DRUG

No Results Yet

NCT05353179 | UNKNOWN | EARLY_PHASE1

88 participants

Study on Pharmacokinetics of Meperizumab Injection and NUCALA® in Healthy Male Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-06-30
Completion:: 2022-10-31

Conditions

Granulomatosis With Polyangiitis
Hemophagocytic Syndrome

Interventions

DRUG

No Results Yet

NCT05353101 | COMPLETED | PHASE1

48 participants

Cyclosporine 0.05% Eye Drops for Vernal Keratoconjunctivitis Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2020-07-01
Completion:: 2021-06-01

Conditions

Vernal Keratoconjunctivitis
Cyclosporine 0.05% Eye Drops

Interventions

DRUG

No Results Yet

NCT05353010 | UNKNOWN | PHASE1

12 participants

A Study to Evaluate Effect of IN-A001 on Pharmacokinetics of Tacrolimus in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-05-01
Completion:: 2022-07-01

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT05352906 | UNKNOWN | NA

300 participants

Accuracy of Handheld and Non-contact Tonometry

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-04-20
Completion:: 2022-12-30

Conditions

Glaucoma
Intraocular Pressure
Glaucoma, Suspect

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05352854 | UNKNOWN | NA

120 participants

Morphological Changes of Ciliary Body and Trabecular Meshwork

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-05-01
Completion:: 2022-06-30

Conditions

Glaucoma
Myopia

Interventions

DRUG

No Results Yet

NCT05352841 | UNKNOWN

40 participants

Leptin, Adiponectin, FRAP and Tac in Patients With Early Childhood Caries

Study Type:: OBSERVATIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-03-30
Completion:: 2022-06-01

Conditions

Early Childhood Caries

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05352620 | COMPLETED | NA

10 participants

Smart Box With OT Equator Attachment in Retaining Implant-assisted Overdenture for the Atrophic Maxilla.

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2018-03-01
Completion:: 2019-05-01

Conditions

Atrophic Maxilla
Edentulous Jaw

Interventions

OTHER

No Results Yet

NCT05352607 | COMPLETED | NA

23 participants

Effect of Transcutaneous Electrical Nerve Stimulation (TENS) on Spasticity in Adult Patients With Spastic Cerebral Palsy

Study Type:: INTERVENTIONAL
Last Updated:: 2022-04-29
Start Date:: 2022-02-01
Completion:: 2022-02-09

Conditions

Cerebral Palsy

Interventions

DEVICE
OTHER

No Results Yet