Clinical Trials

NCT07005297 | NOT_YET_RECRUITING

1000 participants

Clinical Genetics Branch Eligibility Screening Survey

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2035-01-01

Conditions

• Melanoma
• Li-Fraumeni Syndrome
• Pulmonary Blastoma
• Chordoma
• Congenital Bone Marrow Failure Syndromes
• Costello Syndrome
• Fanconi Anemia
• CFC Syndrome (CFCS)
• Legius Syndrome
• RASopathies

No Results Yet

NCT06997809 | RECRUITING | NA

187 participants

ENDometriosis: Evaluation of Detection and Need for ALGOlogic Care Before Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-08-05

Completion:

2030-12-31

Conditions

• Endometriosis, Pain

Interventions

• OTHER

No Results Yet

NCT06997588 | RECRUITING | PHASE2

104 participants

EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-10-09

Completion:

2028-08-02

Conditions

• PIK3CA-related Overgrowth Spectrum (PROS)

Interventions

• DRUG

No Results Yet

NCT06995885 | ENROLLING_BY_INVITATION

30 participants

Development of an Interview-Informed Timeline Follow-Back (TLFB) for Opioid Use in the Era of Fentanyl

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2027-05-31

Conditions

• Substance Use Disorders (SUDs)

No Results Yet

NCT06991751 | NOT_YET_RECRUITING

50 participants

A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2027-08-31

Conditions

• Cardiometabolic Risk Factors
• Mental Health

No Results Yet

NCT06991738 | NOT_YET_RECRUITING | PHASE1/PHASE2

18 participants

177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2032-07-01

Conditions

• Thyroid Cancer

Interventions

• DIAGNOSTIC_TEST
• OTHER
• DRUG

No Results Yet

NCT06989957 | RECRUITING | PHASE1

40 participants

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-09-17

Completion:

2028-08-31

Conditions

• Posttraumatic Stress Disorder

Interventions

• DRUG

No Results Yet

NCT06980519 | TEMPORARILY_NOT_AVAILABLE

MNPR-101-PCTA-177Lu Expanded Access Program (EAP) for Patients With Solid Tumor Cancer

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-09-04

Conditions

• Cancer
• Solid Tumor
• Solid Tumor Cancer
• Oncology
• uPAR-positive Solid Tumor
• Urokinase Plasminogen Activator Receptor-positive Solid Tumor

Interventions

• BIOLOGICAL

No Results Yet

NCT06980506 | TEMPORARILY_NOT_AVAILABLE

MNPR-101-DFO*-89Zr Expanded Access Program (EAP) for Patients With Solid Tumor Cancer

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-09-04

Conditions

• Cancer
• Solid Tumor
• Solid Tumor, Adult

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06973811 | RECRUITING | PHASE2

47 participants

ZR-MTX for PIOL Phase II Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-10-10

Completion:

2027-10-30

Conditions

• Primary Intraocular Lymphoma

Interventions

• DRUG

No Results Yet

NCT06968988 | SUSPENDED | PHASE1

18 participants

Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-01-05

Completion:

2029-02-12

Conditions

• Metastatic Soft-tissue Sarcoma

Interventions

• DRUG

No Results Yet

NCT06968845 | RECRUITING | PHASE2

120 participants

A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-02-02

Completion:

2027-09-30

Conditions

• Idiopathic Pulmonary Fibrosis (IPF)

Interventions

• DRUG
• DEVICE

No Results Yet

NCT06965725 | RECRUITING

22 participants

Paired-Ring Mitral Annuloplasty Ring Sizing Device

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2025-07-03

Completion:

2026-11-30

Conditions

• Heart Valve Diseases

Interventions

• DEVICE

No Results Yet

NCT06959511 | RECRUITING | PHASE2

45 participants

Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-07-22

Completion:

2028-03-01

Conditions

• Neoadjuvant Treatment
• Thyroid Cancer

Interventions

• DRUG

No Results Yet

NCT06957418 | RECRUITING | PHASE2

900 participants

Alzheimer's Tau Platform: Master Protocol

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-07-06

Completion:

2028-08-31

Conditions

• Preclinical Alzheimer's Disease
• Alzheimer Disease
• Prodromal Alzheimer's Disease

Interventions

• DRUG

No Results Yet

NCT06952660 | RECRUITING | PHASE4

100 participants

Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-05-07

Completion:

2028-12-13

Conditions

• Cervical Cancer

Interventions

• DRUG

No Results Yet

NCT06951711 | RECRUITING | PHASE3

274 participants

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-13

Completion:

2026-11-02

Conditions

• Bipolar Disorder Type I With Mania or Mania With Mixed Features

Interventions

• DRUG
• OTHER

No Results Yet

NCT06951698 | RECRUITING | PHASE3

274 participants

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-11

Completion:

2026-11-01

Conditions

• Bipolar-I Disorder With Mania or Mania With Mixed Features

Interventions

• DRUG
• OTHER

No Results Yet

NCT06948214 | RECRUITING | PHASE3

150 participants

Phase 3 Study of LUM-201 in Children With Growth Hormone Deficiency

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-05-20

Completion:

2027-12-31

Conditions

• Growth Hormone Deficiency (GHD)

Interventions

• DRUG
• OTHER

No Results Yet

NCT06948110 | RECRUITING

300 participants

Deciphering the Genetic Architecture of Autoimmune Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2030-04-22

Conditions

• Autoimmune Diseases

No Results Yet

NCT06948097 | RECRUITING | PHASE1

30 participants

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2028-07-14

Conditions

• Lung Transplantation

Interventions

• DRUG

No Results Yet

NCT06942455 | RECRUITING | NA

300 participants

A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-25

Completion:

2029-03-31

Conditions

• Sleep
• Sleep Quality
• Intervention Study
• Ethnic Minority

Interventions

• BEHAVIORAL

No Results Yet

NCT06940752 | ENROLLING_BY_INVITATION | NA

30 participants

VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) Catheters

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2026-12-01

Conditions

• Ventricular Arrhythmia

Interventions

• DEVICE

No Results Yet

NCT06940687 | ACTIVE_NOT_RECRUITING | NA

60 participants

Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-01-28

Completion:

2026-09-22

Conditions

• Alzheimer Disease
• Dementia
• Mild Cognitive Impairment
• Peer-bonded Caregiver
• Caregiver

Interventions

• BEHAVIORAL

No Results Yet

NCT06937099 | RECRUITING | PHASE3

290 participants

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-26

Completion:

2028-05-31

Conditions

• Crohn's Disease
• Obesity or Overweight

Interventions

• DRUG

No Results Yet

NCT06937086 | RECRUITING | PHASE3

350 participants

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-26

Completion:

2028-04-30

Conditions

• Ulcerative Colitis
• Obesity or Overweight

Interventions

• DRUG

No Results Yet

NCT06935071 | ACTIVE_NOT_RECRUITING

300 participants

Endoprosthetic Replacement for Pathological Fractures of the Hip: A 35-year Update

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2016-08-04

Completion:

2027-08-04

Conditions

• Hip Fractures
• Hip Fracture Pathologic
• Pathological Fracture
• Pathological Fracture of Hip

Interventions

• OTHER

No Results Yet

NCT06934642 | RECRUITING | EARLY_PHASE1

8 participants

Effect of Tirzepatide on Markers of MASLD in Patients With Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-30

Completion:

2026-10-31

Conditions

• MASLD
• Obesity

Interventions

• DRUG

No Results Yet

NCT06930651 | RECRUITING | PHASE1/PHASE2

42 participants

A Phase I/II Study of CAR.70-Engineered IL15-Transduced Cord Blood-Derived NK Cells With TGF-beta Receptor 2 (TGFBR2) Knock Out in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Myeloid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-09-03

Completion:

2028-05-01

Conditions

• Myeloid Malignancies

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT06924151 | RECRUITING | NA

450 participants

Isolated Surgical Aortic Valve Replacement in Low Risk AS Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-01

Completion:

2031-05-31

Conditions

• Aortic Stenosis

Interventions

• PROCEDURE

No Results Yet

NCT06912477 | RECRUITING

385 participants

Endothelial Dysfunction for Prognosis In Patients With preeClampSia

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2025-05-08

Completion:

2026-12-31

Conditions

• Preeclampsia (PE)
• Hypertensive Disorder of Pregnancy

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06904066 | RECRUITING | PHASE1

86 participants

Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2029-04-30

Conditions

• Malignancy, Hematologic
• Neoplasms, Hematologic
• Neoplasms, Hematopoietic
• Blood Cancer
• Hematological Neoplasms
• Hematopoietic Malignancies
• Dysmyelopoietic Syndromes
• Hematopoetic Myelodysplasia
• Myeloid Leukemia, Acute
• Nonlymphoblastic Leukemia, Acute
• Leukemia, Lymphocytic, Acute

Interventions

• DRUG
• BIOLOGICAL
• DEVICE

No Results Yet

NCT06902688 | ACTIVE_NOT_RECRUITING | NA

275 participants

Timely Ordering of Pharmacogenetic Testing

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-06-10

Completion:

2026-09-01

Conditions

• Machine Learning
• Prediction Models
• Pediatrics
• Precision Medicine

Interventions

• OTHER

No Results Yet

NCT06901505 | COMPLETED | PHASE3

353 participants

To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-07-24

Completion:

2026-08-12

Conditions

• Anemia of Chronic Kidney Disease

Interventions

• DRUG

No Results Yet

NCT06894225 | RECRUITING | PHASE2

12 participants

Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-03-22

Completion:

2027-05-31

Conditions

• Recurrent Glioblastoma

Interventions

• DRUG

No Results Yet

NCT06891118 | COMPLETED | NA

42 participants

Stellate Ganglion Blockade for Refractory Chronic Migraine

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-03-06

Completion:

2025-12-30

Conditions

• Headache, Migraine
• Chronic Migraine Headache

Interventions

• PROCEDURE

No Results Yet

NCT06890559 | RECRUITING | NA

5120 participants

Enhancing Vaccination Uptake Through Points Redemption Based Financial Incentives and Digital Platforms: an Open-label Cluster Randomized Controlled Trial Utilizing Community Mobilization and Empowerment Strategies

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-07-01

Completion:

2027-07-31

Conditions

• Vaccination Uptake

Interventions

• BEHAVIORAL

No Results Yet

NCT06886529 | ACTIVE_NOT_RECRUITING | NA

1000 participants

PACT Involvement in Cardiology Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-10-16

Completion:

2026-09-01

Conditions

• Machine Learning
• Cardiovascular Outcome
• Pediatric Palliative Care
• Pediatric Cardiology

Interventions

• OTHER

No Results Yet

NCT06886451 | ACTIVE_NOT_RECRUITING | NA

1332 participants

Vomiting Prevention in Children With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-03-18

Completion:

2026-09-02

Conditions

• Chemotherapy Induced Nausea and Vomiting
• Quality of Life (QOL)
• Pediatric Cancer

Interventions

• OTHER

No Results Yet

NCT06883188 | NOT_YET_RECRUITING | PHASE2/PHASE3

30 participants

Stop Air Leak by Talc or Autologous Blood Patch Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-11-01

Completion:

2029-10-31

Conditions

• Pneumothorax Spontaneous Secondary

Interventions

• DRUG
• BIOLOGICAL

No Results Yet