Clinical Trials

NCT06191978 | RECRUITING | PHASE1

40 participants

A Phase Ia/Ib Open-label, Multiple Dose, Study to Determine the Recommended Dose, Evaluate PKs, PDs, Safety, and Activity of Venetoclax in Combination With Oral Decitabine/Cedazuridine (ASTX727) in Pediatric Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-03-07

Completion:

2028-12-31

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT06178471 | WITHDRAWN

0 participants

Safety, Feasibility and Clinical Utility of Critical Care Transesophageal Echocardiography in Hong Kong

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2025-09-08

Completion:

2026-01-01

Conditions

• Cardiopulmonary Failure

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06172296 | RECRUITING | PHASE3

478 participants

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-04-19

Completion:

2029-12-31

Conditions

• Ganglioneuroblastoma, Nodular
• Neuroblastoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION
• OTHER

No Results Yet

NCT06167486 | COMPLETED | PHASE1

17 participants

SG2918 For Advanced Malignant Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-12-26

Completion:

2025-11-11

Conditions

• Advanced Malignant Tumors

Interventions

• DRUG

No Results Yet

NCT06161402 | ACTIVE_NOT_RECRUITING | NA

62 participants

Elastic Band-Progressive Resistance Training (EB-PRT) for Sarcopenia Among Heart Failure Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-12-01

Completion:

2025-12-31

Conditions

• Heart Failure

Interventions

• BEHAVIORAL

No Results Yet

NCT06160128 | RECRUITING

400000 participants

Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2022-09-26

Completion:

2026-09-30

Conditions

• COVID-19, SARS-CoV-2 Infection
• RSV
• Influenza

No Results Yet

NCT06146543 | COMPLETED | NA

100 participants

Stress Ball During Lumbar Puncture the Effect of the Application on Anxiety Level

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-01

Completion:

2024-08-22

Conditions

• Neurologic Disorder

Interventions

• OTHER

No Results Yet

NCT06144359 | COMPLETED | NA

59 participants

Diffusion Tensor Brain MRI in the Detection of Structural Abnormality of the White Substance in Concussion

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-22

Completion:

2025-10-17

Conditions

• Concussion, Brain

Interventions

• OTHER

No Results Yet

NCT06132113 | ACTIVE_NOT_RECRUITING | PHASE1

65 participants

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-01-22

Completion:

2027-10-09

Conditions

• Neuroendocrine Neoplasms

Interventions

• DRUG

No Results Yet

NCT06128018 | RECRUITING | NA

70 participants

Comparing Endoscopic Ultrasound vs Surgical Gastrojejunostomy for Management of GOO.

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-11-01

Completion:

2026-09-08

Conditions

• Malignant Gastric Outlet Obstruction

Interventions

• PROCEDURE

No Results Yet

NCT06127511 | COMPLETED | NA

142 participants

Peanut Consumption on Cognitive, Weight, and Inflammation

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-01-29

Completion:

2025-06-30

Conditions

• Cognitive Performance
• Inflammation
• Weight Change, Body
• Adolescents

Interventions

• OTHER

No Results Yet

NCT06126276 | RECRUITING | PHASE2

70 participants

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-05-07

Completion:

2027-02-20

Conditions

• Malignant Female Reproductive System Neoplasm
• Malignant Solid Neoplasm
• Recurrent Malignant Female Reproductive System Neoplasm
• Recurrent Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT06126224 | RECRUITING | PHASE3

500 participants

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-08-28

Completion:

2026-12-09

Conditions

• Psychosis Associated With Alzheimer's Disease

Interventions

• DRUG

No Results Yet

NCT06125743 | RECRUITING | NA

204 participants

Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-03-29

Completion:

2027-08-31

Conditions

• Lymphedema of the Head and Neck

Interventions

• BEHAVIORAL

No Results Yet

NCT06124157 | RECRUITING | PHASE2

222 participants

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2025-05-30

Completion:

2030-12-01

Conditions

• B Acute Lymphoblastic Leukemia

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG
• RADIATION

No Results Yet

NCT06112860 | RECRUITING | NA

50 participants

OTC Hearing Aid and MCI

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-07-23

Completion:

2026-12-31

Conditions

• Hearing Loss
• Mild Cognitive Impairment
• Alzheimer Disease and Related Dementias (ADRD)

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT06112613 | ACTIVE_NOT_RECRUITING | NA

390 participants

Mobile Health for Adherence in Breast Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-04-02

Completion:

2027-09-22

Conditions

• Breast Carcinoma

Interventions

• OTHER
• PROCEDURE
• BEHAVIORAL

No Results Yet

NCT06096844 | RECRUITING | PHASE3

304 participants

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-07-19

Completion:

2039-04-01

Conditions

• Advanced Lung Non-Small Cell Carcinoma
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL
• OTHER

No Results Yet

NCT06096597 | RECRUITING | PHASE2/PHASE3

100 participants

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-07-24

Completion:

2027-05-01

Conditions

• Interstitial Cystitis
• Painful Bladder Syndrome
• Painful Bladder Syndrome (PBS)

Interventions

• DRUG

No Results Yet

NCT06095388 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

15 participants

Phase I/II Study of JR-441 in Patients With Mucopolysaccharidosis Type IIIA

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-04

Completion:

2029-10-31

Conditions

• Mucopolysaccharidosis III-A

Interventions

• DRUG

No Results Yet

NCT06094387 | TERMINATED

2 participants

The Use of Thrombin Generation Assay in Detection of Central Line Related Thrombosis (CRT) in Critically Ill Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2024-04-06

Completion:

2024-12-01

Conditions

• Central Line Complication
• Thrombosis, Venous

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06092827 | COMPLETED | NA

12 participants

Feasibility and Acceptability of Non Weight-bearing Physical Activity for People With Diabetic Foot Ulceration

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-12-01

Completion:

2025-02-28

Conditions

• Diabetic Foot
• Cardiopulmonary
• Physical Inactivity

Interventions

• BEHAVIORAL

No Results Yet

NCT06077500 | ACTIVE_NOT_RECRUITING | PHASE1

46 participants

DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-02-14

Completion:

2026-09-01

Conditions

• Small Cell Lung Carcinoma (SCLC)

Interventions

• DRUG

No Results Yet

NCT06077201 | RECRUITING | NA

240 participants

Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-12-15

Completion:

2027-02-01

Conditions

• Valvular Heart Disease

Interventions

• OTHER

No Results Yet

NCT06076291 | COMPLETED | PHASE1

19 participants

An Open-label Study of SG1827 in Subjects With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-27

Completion:

2026-03-18

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06076187 | COMPLETED

66 participants

Protein Digestion After Bariatric Surgery in Older Adults

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2023-05-15

Completion:

2026-04-01

Conditions

• Overweight and Obesity
• Bariatric Surgery Candidate
• Aging
• Protein Malabsorption

Interventions

• OTHER

No Results Yet

NCT06072924 | RECRUITING | NA

70 participants

K01 Impacts of Lingual Endurance Exercise

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-01

Completion:

2027-08-31

Conditions

• Dysphagia
• Dysphagia, Oropharyngeal
• Ischemic Stroke
• Stroke

Interventions

• BEHAVIORAL

No Results Yet

NCT06064097 | RECRUITING | PHASE2

50 participants

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-06-25

Completion:

2027-03-31

Conditions

• Stage II Nasopharyngeal Carcinoma AJCC v8
• Stage III Nasopharyngeal Carcinoma AJCC v8
• Stage IV Nasopharyngeal Carcinoma AJCC v8

Interventions

• PROCEDURE
• DRUG
• OTHER
• BIOLOGICAL
• RADIATION

No Results Yet

NCT06062966 | COMPLETED | PHASE1

4 participants

The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-02-05

Completion:

2026-06-01

Conditions

• Heart Failure

Interventions

• DRUG

No Results Yet

NCT06062498 | RECRUITING | PHASE2

174 participants

Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-29

Completion:

2028-07-01

Conditions

• Estrogen-receptor-positive Breast Cancer
• HER2/Neu-Negative Breast Cancer
• Advanced Breast Cancerv
• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06058377 | RECRUITING | PHASE3

3680 participants

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-11-27

Completion:

2032-05-31

Conditions

• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• HER2-Negative Breast Carcinoma
• Hormone Receptor-Positive Breast Carcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT06055725 | ACTIVE_NOT_RECRUITING

1057 participants

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2023-11-01

Completion:

2027-11-30

Conditions

• Spasticity as Sequela of Stroke

No Results Yet

NCT06053697 | ACTIVE_NOT_RECRUITING

120 participants

Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies?

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2022-07-05

Completion:

2027-04-30

Conditions

• Preterm Birth
• Preterm Labor
• Multiple; Pregnancy, Complicated
• Twin Dichorionic Diamniotic Placenta
• Twin Monochorionic Monoamniotic Placenta
• Twin; Pregnancy, Affecting Fetus or Newborn
• Vaginal Microbiome
• Cervical Stiffness

No Results Yet

NCT06052631 | NOT_YET_RECRUITING

16 participants

Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals With Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 Gene

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2026-12-31

Conditions

• PIEZO2-Deficiency Syndrome

No Results Yet

NCT06050252 | SUSPENDED | PHASE2

27 participants

Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-07-10

Completion:

2027-02-12

Conditions

• Resectable Intrahepatic Cholangiocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT06049290 | RECRUITING | PHASE1/PHASE2

342 participants

A Clinical Trial of LBL-034 in Patients With Relapsed Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-20

Completion:

2026-10-20

Conditions

• Relapsed/Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06047457 | ACTIVE_NOT_RECRUITING | PHASE3

751 participants

A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Episodic Migraine in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-29

Completion:

2026-06-01

Conditions

• Episodic Migraine

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06047444 | ACTIVE_NOT_RECRUITING | PHASE3

759 participants

A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-12

Completion:

2026-05-28

Conditions

• Chronic Migraine

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06044935 | RECRUITING | NA

100 participants

Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-01-08

Completion:

2027-01-31

Conditions

• Overweight
• Obesity

Interventions

• OTHER
• DIETARY_SUPPLEMENT

No Results Yet

NCT06043323 | RECRUITING | PHASE2

20 participants

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-01-08

Completion:

2028-09-01

Conditions

• Follicular Lymphoma

Interventions

• DRUG

No Results Yet