Clinical Trials

NCT06096844 | RECRUITING | PHASE3

304 participants

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-07-19

Completion:

2039-04-01

Conditions

• Advanced Lung Non-Small Cell Carcinoma
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL
• OTHER

No Results Yet

NCT06096597 | RECRUITING | PHASE2/PHASE3

100 participants

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-07-24

Completion:

2027-05-01

Conditions

• Interstitial Cystitis
• Painful Bladder Syndrome
• Painful Bladder Syndrome (PBS)

Interventions

• DRUG

No Results Yet

NCT06095388 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

15 participants

Phase I/II Study of JR-441 in Patients With Mucopolysaccharidosis Type IIIA

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-04

Completion:

2029-10-31

Conditions

• Mucopolysaccharidosis III-A

Interventions

• DRUG

No Results Yet

NCT06094387 | TERMINATED

2 participants

The Use of Thrombin Generation Assay in Detection of Central Line Related Thrombosis (CRT) in Critically Ill Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2024-04-06

Completion:

2024-12-01

Conditions

• Central Line Complication
• Thrombosis, Venous

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06092827 | COMPLETED | NA

12 participants

Feasibility and Acceptability of Non Weight-bearing Physical Activity for People With Diabetic Foot Ulceration

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-12-01

Completion:

2025-02-28

Conditions

• Diabetic Foot
• Cardiopulmonary
• Physical Inactivity

Interventions

• BEHAVIORAL

No Results Yet

NCT06077500 | ACTIVE_NOT_RECRUITING | PHASE1

46 participants

DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-02-14

Completion:

2026-09-01

Conditions

• Small Cell Lung Carcinoma (SCLC)

Interventions

• DRUG

No Results Yet

NCT06077201 | RECRUITING | NA

240 participants

Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-12-15

Completion:

2027-02-01

Conditions

• Valvular Heart Disease

Interventions

• OTHER

No Results Yet

NCT06076291 | COMPLETED | PHASE1

19 participants

An Open-label Study of SG1827 in Subjects With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-27

Completion:

2026-03-18

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT06076187 | COMPLETED

66 participants

Protein Digestion After Bariatric Surgery in Older Adults

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2023-05-15

Completion:

2026-04-01

Conditions

• Overweight and Obesity
• Bariatric Surgery Candidate
• Aging
• Protein Malabsorption

Interventions

• OTHER

No Results Yet

NCT06072924 | RECRUITING | NA

70 participants

K01 Impacts of Lingual Endurance Exercise

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-01

Completion:

2027-08-31

Conditions

• Dysphagia
• Dysphagia, Oropharyngeal
• Ischemic Stroke
• Stroke

Interventions

• BEHAVIORAL

No Results Yet

NCT06064097 | RECRUITING | PHASE2

50 participants

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-06-25

Completion:

2027-03-31

Conditions

• Stage II Nasopharyngeal Carcinoma AJCC v8
• Stage III Nasopharyngeal Carcinoma AJCC v8
• Stage IV Nasopharyngeal Carcinoma AJCC v8

Interventions

• PROCEDURE
• DRUG
• OTHER
• BIOLOGICAL
• RADIATION

No Results Yet

NCT06062966 | COMPLETED | PHASE1

4 participants

The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART)

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-02-05

Completion:

2026-06-01

Conditions

• Heart Failure

Interventions

• DRUG

No Results Yet

NCT06062498 | RECRUITING | PHASE2

174 participants

Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-29

Completion:

2028-07-01

Conditions

• Estrogen-receptor-positive Breast Cancer
• HER2/Neu-Negative Breast Cancer
• Advanced Breast Cancerv
• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06058377 | RECRUITING | PHASE3

3680 participants

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-11-27

Completion:

2032-05-31

Conditions

• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• HER2-Negative Breast Carcinoma
• Hormone Receptor-Positive Breast Carcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT06055725 | ACTIVE_NOT_RECRUITING

1057 participants

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2023-11-01

Completion:

2027-11-30

Conditions

• Spasticity as Sequela of Stroke

No Results Yet

NCT06053697 | ACTIVE_NOT_RECRUITING

120 participants

Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies?

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2022-07-05

Completion:

2027-04-30

Conditions

• Preterm Birth
• Preterm Labor
• Multiple; Pregnancy, Complicated
• Twin Dichorionic Diamniotic Placenta
• Twin Monochorionic Monoamniotic Placenta
• Twin; Pregnancy, Affecting Fetus or Newborn
• Vaginal Microbiome
• Cervical Stiffness

No Results Yet

NCT06052631 | NOT_YET_RECRUITING

16 participants

Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals With Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 Gene

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2026-09-09

Completion:

2026-12-31

Conditions

• PIEZO2-Deficiency Syndrome

No Results Yet

NCT06050252 | SUSPENDED | PHASE2

27 participants

Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-07-10

Completion:

2027-02-12

Conditions

• Resectable Intrahepatic Cholangiocarcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT06049290 | RECRUITING | PHASE1/PHASE2

342 participants

A Clinical Trial of LBL-034 in Patients With Relapsed Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-20

Completion:

2026-10-20

Conditions

• Relapsed/Refractory Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06047457 | ACTIVE_NOT_RECRUITING | PHASE3

751 participants

A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Episodic Migraine in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-29

Completion:

2026-06-01

Conditions

• Episodic Migraine

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06047444 | ACTIVE_NOT_RECRUITING | PHASE3

759 participants

A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-12

Completion:

2026-05-28

Conditions

• Chronic Migraine

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT06044935 | RECRUITING | NA

100 participants

Effect of Nicotinamide Riboside on Ketosis, Fat Oxidation & Metabolic Rate

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-01-08

Completion:

2027-01-31

Conditions

• Overweight
• Obesity

Interventions

• OTHER
• DIETARY_SUPPLEMENT

No Results Yet

NCT06043323 | RECRUITING | PHASE2

20 participants

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-01-08

Completion:

2028-09-01

Conditions

• Follicular Lymphoma

Interventions

• DRUG

No Results Yet

NCT06014502 | RECRUITING | PHASE1

105 participants

Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-07

Completion:

2027-12-31

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05999032 | RECRUITING | NA

480 participants

The Puerto Rico Asthma Integrated Response Program ("PR-AIR")

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-12-16

Completion:

2026-11-30

Conditions

• Pediatric Asthma

Interventions

• BEHAVIORAL

No Results Yet

NCT05995886 | RECRUITING | NA

60 participants

Using Facebook to Support Opioid Recovery Among American Indian Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-16

Completion:

2026-10-12

Conditions

• Opioid Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05991453 | RECRUITING | NA

13000 participants

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-13

Completion:

2027-07-31

Conditions

• Surgery-Complications
• Anesthesia Complication
• Anesthesia Awareness
• Anesthesia
• Surgery
• Quality of Life
• Pain, Postoperative
• Anesthesia Morbidity

Interventions

• OTHER

No Results Yet

NCT05990946 | RECRUITING | NA

736 participants

Smartphone-based Remote Symptom Monitoring to Improve Postoperative Rehabilitation Exercise Adherence After Video-assisted Thoracic Surgery (VATS) for Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-12-01

Completion:

2027-03-30

Conditions

• Lung Neoplasms, Non-Small Cell Lung Cancer
• Postoperative Complications
• Patient Reported Outcome Measures
• Telerehabilitation
• Exercise Therapy

Interventions

• DEVICE

No Results Yet

NCT05987241 | RECRUITING | PHASE2/PHASE3

992 participants

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-02-02

Completion:

2030-09-02

Conditions

• Muscle Invasive Bladder Urothelial Carcinoma
• Muscle Invasive Renal Pelvis Urothelial Carcinoma
• Muscle Invasive Ureter Urothelial Carcinoma
• Muscle Invasive Urethral Urothelial Carcinoma
• Stage II Bladder Urothelial Carcinoma AJCC v6 and v7
• Stage III Bladder Urothelial Carcinoma AJCC v6 and v7
• Stage IV Bladder Urothelial Carcinoma AJCC v7

Interventions

• PROCEDURE
• OTHER
• BIOLOGICAL

No Results Yet

NCT05985681 | RECRUITING | PHASE1

18 participants

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2026-01-27

Completion:

2028-02-01

Conditions

• Human Papillomavirus-Related Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• OTHER

No Results Yet

NCT05978557 | RECRUITING

50 participants

Brain Slice Explants to Predict Drug Response in Brain Tumors

Study Type:

OBSERVATIONAL

Last Updated:

2026-09-04

Start Date:

2023-07-27

Completion:

2028-03-01

Conditions

• Central Nervous System Tumor

Interventions

• OTHER

No Results Yet

NCT05978336 | RECRUITING | NA

290 participants

SuPA Mobility: Supporting Physical Activity for Mobility in Mobility-Limited Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-05

Completion:

2027-06-30

Conditions

• Limitation, Mobility
• Older Adults

Interventions

• BEHAVIORAL

No Results Yet

NCT05973955 | COMPLETED | NA

70 participants

Adapting CBT-I for Hazardous Alcohol Users

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-03-22

Completion:

2026-08-31

Conditions

• Insomnia
• Harmful; Use, Alcohol

Interventions

• BEHAVIORAL

No Results Yet

NCT05967572 | COMPLETED | NA

84 participants

The Effect of Different Music Listened During Retinopathy Examination to Premature Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-06-01

Completion:

2024-03-01

Conditions

• Retinopathy of Prematurity
• Newborn

Interventions

• OTHER

No Results Yet

NCT05952024 | RECRUITING | PHASE2

80 participants

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-07-16

Completion:

2029-04-22

Conditions

• Diffuse Large B-Cell Lymphoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05950425 | COMPLETED | NA

84 participants

Aspiration Training Given With Different Methods

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-07-10

Completion:

2024-05-01

Conditions

• Aspiration
• Pediatric Intensive Care Unit

Interventions

• OTHER

No Results Yet

NCT05933174 | RECRUITING | NA

220 participants

Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-10-01

Completion:

2027-06-30

Conditions

• Type2diabetes

Interventions

• OTHER

No Results Yet

NCT05919368 | ACTIVE_NOT_RECRUITING | NA

192 participants

Effects of Shanyu Pill in Older Adults With Sarcopenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-07-17

Completion:

2024-12-10

Conditions

• Sarcopenia

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05911256 | ENROLLING_BY_INVITATION | NA

318 participants

A Community Health Worker/Pharmacist Team to Improve Blood Sugars in Diabetes Care Using Continuous Glucose Monitoring

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2024-09-27

Completion:

2028-03-31

Conditions

• Type 2 Diabetes

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT05907564 | ACTIVE_NOT_RECRUITING | NA

120 participants

Aventus Thrombectomy System Pulmonary Embolism Clinical Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-09-04

Start Date:

2023-09-20

Completion:

2025-02-20

Conditions

• Pulmonary Embolism
• Embolism
• Embolism and Thrombosis
• Vascular Diseases
• Cardiovascular Diseases
• Lung Diseases
• Respiratory Tract Diseases

Interventions

• DEVICE

Results Available