Clinical Trials Updated in 2026

NCT05711394 | RECRUITING | PHASE3

450 participants

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-05-01
Completion:: 2028-03-31

Conditions

Episodic Migraine

Interventions

DRUG

No Results Yet

NCT05691478 | SUSPENDED | PHASE2/PHASE3

1122 participants

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-03-03
Completion:: 2030-03-20

Conditions

High Grade Osteosarcoma
Localized Osteosarcoma
Metastatic Osteosarcoma
Secondary Osteosarcoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05687123 | RECRUITING | PHASE1

24 participants

Testing the Addition of Sunitinib Malate to Lutetium Lu 177 Dotatate (Lutathera) in Pancreatic Neuroendocrine Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-08-14
Completion:: 2026-12-14

Conditions

Metastatic Pancreatic Neuroendocrine Tumor
Pancreatic Neoplasm
Stage III Pancreatic Neuroendocrine Tumor AJCC v8
Stage IV Pancreatic Neuroendocrine Tumor AJCC v8
Unresectable Pancreatic Neuroendocrine Tumor

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05677490 | RECRUITING | PHASE3

382 participants

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-01-31
Completion:: 2028-11-08

Conditions

Advanced Esophageal Adenocarcinoma
Advanced Gastric Adenocarcinoma
Advanced Gastroesophageal Junction Adenocarcinoma
Clinical Stage III Esophageal Adenocarcinoma AJCC v8
Clinical Stage III Gastric Cancer AJCC v8
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
Clinical Stage IV Gastric Cancer AJCC v8
Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8
Metastatic Esophageal Adenocarcinoma
Metastatic Gastric Adenocarcinoma
Metastatic Gastroesophageal Junction Adenocarcinoma
Unresectable Esophageal Adenocarcinoma
Unresectable Gastric Adenocarcinoma
Unresectable Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG
BIOLOGICAL
PROCEDURE
OTHER

No Results Yet

NCT05677256 | COMPLETED | PHASE4

501 participants

A Study to Evaluate Pharyngeal Immunity to Poliovirus Type-2

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-11-09
Completion:: 2024-02-20

Conditions

Poliomyelitis

Interventions

BIOLOGICAL

Results Available

NCT05673187 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-06-12
Completion:: 2025-07-28

Conditions

NSCLC Stage IV
KRAS P.G12C

Interventions

DRUG

No Results Yet

NCT05673148 | RECRUITING | PHASE2

146 participants

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-10-09
Completion:: 2028-07-03

Conditions

Metastatic Colorectal Adenocarcinoma
Stage IV Colorectal Cancer AJCC v8
Oligometastatic Colorectal Carcinoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05662228 | COMPLETED | PHASE2

66 participants

Therapies for Down Syndrome Regression Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-06-29
Completion:: 2026-05-05

Conditions

Down Syndrome
Regression

Interventions

DRUG

No Results Yet

NCT05654246 | RECRUITING

200000 participants

Susan G. Komen's ShareForCures

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-11-17
Completion:: 2032-11-30

Conditions

Breast Cancer

No Results Yet

NCT05652400 | COMPLETED

2200 participants

HIV Transmission in the Era of Scaling up Antiretroviral Therapy in Ethiopia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-07-01
Completion:: 2024-12-31

Conditions

HIV-1-infection
Antiretroviral Therapy

Interventions

OTHER

No Results Yet

NCT05617755 | ACTIVE_NOT_RECRUITING | PHASE1

19 participants

AB-1015, an Integrated Circuit T (ICT) Cell Therapy in Patients With Platinum Resistant Epithelial Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-11-29
Completion:: 2024-09-30

Conditions

Carcinoma, Ovarian Epithelial
Ovarian Neoplasms
Fallopian Tube Neoplasms
Peritoneal Neoplasms
Neoplasms, Glandular and Epithelial
Ovarian Diseases
Genital Neoplasm, Female
Abdominal Neoplasm
Recurrence

Interventions

BIOLOGICAL

No Results Yet

NCT05616650 | RECRUITING | PHASE2

42 participants

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-10-19
Completion:: 2030-12-01

Conditions

Prostatic Neoplasms
Prostate Cancer
Prostate Adenocarcinoma

Interventions

DRUG
RADIATION

No Results Yet

NCT05615844 | RECRUITING | PHASE3

312 participants

Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-11-05
Completion:: 2027-03-31

Conditions

Open tíbia Fracture

Interventions

DRUG
DEVICE

No Results Yet

NCT05613010 | ACTIVE_NOT_RECRUITING | NA

65 participants

Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-03-19
Completion:: 2027-08-30

Conditions

Transplant;Failure,Kidney
Transplant; Failure, Liver
Adherence, Medication
Adherence, Patient
Adherence, Treatment

Interventions

BEHAVIORAL

No Results Yet

NCT05604066 | COMPLETED | NA

72 participants

Magnetic Resonance Elastography of Myofascial Pain Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-04-13
Completion:: 2025-08-31

Conditions

Myofascial Pain

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05599360 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Vyxeos for Induction of Low- or Intermediate-risk.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-08-07
Completion:: 2023-10-23

Conditions

Leukemia, Myeloid, Acute

Interventions

DRUG

Results Available

NCT05590949 | RECRUITING

100 participants

Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-10-18
Completion:: 2026-10-18

Conditions

Breast Cancer

Interventions

OTHER
DIAGNOSTIC_TEST

No Results Yet

NCT05588128 | RECRUITING

350 participants

Prospective Monitoring of Subjects With Biochemically Recurrent Prostate Cancer Using 18FDCFPyL

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-03-21
Completion:: 2026-12-31

Conditions

Prostate Cancer
Biochemically Recurrent

Interventions

DRUG

No Results Yet

NCT05583617 | RECRUITING | PHASE1/PHASE2

200 participants

A Study Evaluating the Safety and Efficacy of Multiple Treatments in Participants With Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-11-14
Completion:: 2028-07-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05568225 | TERMINATED | PHASE2

17 participants

A Study of Etavopivat for the Treatment of Anemia in Patients With Myelodysplastic Syndromes (MDS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-11-15
Completion:: 2024-07-15

Conditions

Very Low Risk, Low Risk, or Intermediate Risk MDS Per IPSS-R

Interventions

DRUG

Results Available

NCT05568095 | COMPLETED | PHASE3

1040 participants

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-11-21
Completion:: 2026-08-28

Conditions

Advanced Upper Gastrointestinal Tract Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05564390 | RECRUITING | PHASE2

2000 participants

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2024-06-18
Completion:: 2029-05-15

Conditions

Acute Myeloid Leukemia
Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm
Acute Myeloid Leukemia Post Cytotoxic Therapy
Acute Myeloid Leukemia, Myelodysplasia-Related
Myelodysplastic Syndrome

Interventions

PROCEDURE
DRUG
OTHER
BIOLOGICAL
RADIATION

No Results Yet

NCT05564377 | RECRUITING | PHASE2

2900 participants

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-04-07
Completion:: 2030-07-01

Conditions

Advanced Malignant Solid Neoplasm
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Locally Advanced Malignant Solid Neoplasm
Malignant Female Reproductive System Neoplasm
Metastatic HER2-Negative Breast Carcinoma
Metastatic Malignant Solid Neoplasm
Recurrent Endometrial Carcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Malignant Female Reproductive System Neoplasm
Recurrent Malignant Solid Neoplasm
Recurrent Ovarian Carcinoma
Recurrent Primary Peritoneal Carcinoma
Unresectable HER2-Negative Breast Carcinoma
Unresectable Malignant Solid Neoplasm

Interventions

DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT05559749 | ACTIVE_NOT_RECRUITING | NA

60 participants

Collaborative Care for Anxiety and Depression in Epilepsy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-05-04
Completion:: 2027-03-31

Conditions

Epilepsy
Anxiety
Depression

Interventions

BEHAVIORAL

No Results Yet

NCT05554107 | RECRUITING | NA

200 participants

The Effect of Physical Activity on Postural Orthostatic Tachycardia Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-11-02
Completion:: 2028-03-31

Conditions

POTS - Postural Orthostatic Tachycardia Syndrome

Interventions

OTHER

No Results Yet

NCT05551221 | COMPLETED | PHASE4

110 participants

The Efficacy and Safety of Silodosin in the Treatment of Benign Prostatic Hyperplasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-09-21
Completion:: 2024-09-10

Conditions

Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms

Interventions

DRUG

No Results Yet

NCT05542121 | COMPLETED | NA

27 participants

Rehab CARES In USA: Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-06-01
Completion:: 2025-08-30

Conditions

Stroke
Hemiplegia

Interventions

DEVICE
OTHER

No Results Yet

NCT05533775 | RECRUITING | PHASE1/PHASE2

65 participants

A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-11-16
Completion:: 2029-11-30

Conditions

Mature B-Cell Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05522023 | COMPLETED | NA

110 participants

Effects of Aromatic Solution Applied After Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2021-02-15
Completion:: 2023-05-15

Conditions

Surgery
Nurse's Role
Throat, Sore
Thirst
Nausea and Vomiting, Postoperative

Interventions

PROCEDURE

No Results Yet

NCT05521997 | NOT_YET_RECRUITING | PHASE2

42 participants

Glutaminase Inhibition and Chemoradiation in Advanced Cervical Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2026-12-31
Completion:: 2033-03-07

Conditions

Advanced Cervical Carcinoma
Cervical Cancer
Cervix Cancer
Cancer of the Cervix

Interventions

DRUG
RADIATION

No Results Yet

NCT05518045 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

392 participants

A Study of LM-108 as Monotherapy or in Combination With Antitumor Therapies in Subjects With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-08-26
Completion:: 2026-10-31

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT05515575 | ACTIVE_NOT_RECRUITING | PHASE2

8 participants

A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-08-23
Completion:: 2027-08-31

Conditions

Sarcoma,Soft Tissue
Sarcoma Uterus

Interventions

DRUG

No Results Yet

NCT05511597 | COMPLETED | NA

26 participants

Split-belt Treadmill Training for Freezing of Gait in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-12-16
Completion:: 2025-10-31

Conditions

Parkinson Disease
Freezing of Gait
Split-belt Treadmill

Interventions

BEHAVIORAL

No Results Yet

NCT05503862 | COMPLETED | NA

106 participants

Home Semen Testing in Men Beginning Attempts to Conceive

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-08-17
Completion:: 2025-06-18

Conditions

Male Infertility

Interventions

DEVICE

Results Available

NCT05491980 | ACTIVE_NOT_RECRUITING

72 participants

Florida Cerebrovascular Disease Biorepository and Genomics Center

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-08-02
Completion:: 2030-06-30

Conditions

Cerebrovascular Disease
Ischemic Stroke
Transient Ischemic Attack
Intracerebral Hemorrhage
Aneurysmal Subarachnoid Hemorrhage
Vascular Dementia
Anoxic Brain Injury
Unruptured Intracranial Aneurysm
Carotid Artery Stenosis Symptomatic
Asymptomatic Carotid Artery Stenosis
Non-Aneurysmal Perimesencephalic Subarachnoid Haemorrhage
Cerebral Venous Thrombosis
Moyamoya Disease
Fibromuscular Dysplasia
Subarachnoid Hemorrhage
Leukoaraiosis
Arteriovenous Fistula
Reversible Cerebral Vasoconstriction Syndrome
CADASIL

No Results Yet

NCT05466422 | COMPLETED | PHASE1

34 participants

A Study of MK-2214 in Adults With Mild Cognitive Impairment or Mild-to-Moderate Alzheimer's Disease (MK-2214-002)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-09-20
Completion:: 2025-07-03

Conditions

Alzheimer Disease

Interventions

BIOLOGICAL
DRUG

Results Available

NCT05459155 | COMPLETED | NA

1485 participants

Effect of Synapse Medicine Decision Support on Inpatient Pharmacist Efficacy and Efficiency

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-05-31
Completion:: 2024-10-30

Conditions

Infections
Heart Diseases
Lung Diseases
Kidney Diseases
Liver Diseases
Gastrointestinal Diseases

Interventions

OTHER

No Results Yet

NCT05457946 | COMPLETED | PHASE2/PHASE3

60 participants

Study to Evaluate the Immunogenicity and Safety of LBVD(Hexavalent Vaccine), Given to Healthy Infants at Primary Series

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2018-07-18
Completion:: 2019-02-21

Conditions

Diphtheria
Tetanus
Pertussis
Hepatitis B
Poliomyelitis
Haemophilus Influenzae Type B Infection

Interventions

BIOLOGICAL

No Results Yet

NCT05437705 | RECRUITING | NA

40 participants

Decoding and Modulating Affective Brain States

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-03
Start Date:: 2023-02-21
Completion:: 2028-12-01

Conditions

Rumination
Major Depressive Disorder
Anxiety

Interventions

DEVICE

No Results Yet

NCT05413291 | RECRUITING

4000 participants

Natural History Protocol for Movement Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-03
Start Date:: 2022-10-17
Completion:: 2030-12-31

Conditions

Movement Disorder
Tremor
Parkinson's Disease

No Results Yet