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Clinical Trials

Showing trials with last updates posted in 2026.

NCT05319730 | RECRUITING | PHASE1/PHASE2
230 participants

A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2023-05-16
Completion:
2027-06-11
Conditions
  • Esophageal Squamous Cell Carcinoma
Interventions
  • DRUG
  • BIOLOGICAL
No Results Yet
NCT05286814 | RECRUITING | PHASE2
70 participants

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2022-10-24
Completion:
2027-12-31
Conditions
  • Metastatic Colorectal Cancer (Mcrc)
  • Intrahepatic Cholangiocarcinoma (Icc)
  • Intrahepatic Bile Duct Cancer
  • Colorectal Neoplasms
  • Colorectal Cancer
  • Cholangiocarcinoma
  • Bile Duct Neoplasms
  • Bile Duct Cancer
  • Adrenocortical Carcinoma (ACC)
  • Adrenal Cortical Carcinoma
  • Adrenal Gland Cancer
  • Adrenal Gland Neoplasms
  • Adrenal Cortex Neoplasms
Interventions
  • DRUG
  • DEVICE
No Results Yet
NCT05245500 | RECRUITING | PHASE1
336 participants

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2022-06-09
Completion:
2027-12-10
Conditions
  • Mesothelioma
  • Non Small Cell Lung Cancer
  • Malignant Peripheral Nerve Sheath Tumors
  • Solid Tumor
  • Pancreatic Adenocarcinoma
  • Advanced Solid Tumor
Interventions
  • DRUG
No Results Yet
NCT05224154 | COMPLETED | NA
9 participants

Re-Connect Application for Smoking Cessation

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2021-12-14
Completion:
2026-02-28
Conditions
  • Smoking Cessation
  • Acceptability of Health Care
  • Nicotine Dependence, Cigarettes
Interventions
  • BEHAVIORAL
No Results Yet
NCT05028309 | RECRUITING | NA
72 participants

Effects of Obesity in the Aged

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2021-12-01
Completion:
2026-12-31
Conditions
  • Obesity
  • Aging
Interventions
  • OTHER
No Results Yet
NCT04981509 | RECRUITING | PHASE2
65 participants

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2022-06-10
Completion:
2027-12-31
Conditions
  • Hereditary Leiomyomatosis and Renal Cell Carcinoma
  • Papillary Renal Cell Carcinoma
  • Renal Cell Carcinoma
  • Sporadic Papillary Renal Cell Carcinoma
  • Stage III Renal Cell Cancer AJCC v8
  • Stage IV Renal Cell Cancer AJCC v8
Interventions
  • BIOLOGICAL
  • PROCEDURE
  • DRUG
No Results Yet
NCT04934722 | COMPLETED | PHASE3
186 participants

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)-China Extension

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2021-05-25
Completion:
2022-10-31
Conditions
  • Metastatic Hormone-Sensitive Prostate Cancer
Interventions
  • BIOLOGICAL
  • DRUG
  • OTHER
Results Available
NCT04930653 | RECRUITING | PHASE2
34 participants

Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2022-10-19
Completion:
2028-06-15
Conditions
  • Folliculotropic Mycosis Fungoides
  • Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
  • Sezary Syndrome
  • Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v8
  • Stage II Mycosis Fungoides and Sezary Syndrome AJCC v8
  • Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v8
  • Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v8
  • Transformed Mycosis Fungoides
Interventions
  • PROCEDURE
  • BIOLOGICAL
  • OTHER
No Results Yet
NCT04902508 | ACTIVE_NOT_RECRUITING | NA
111 participants

Evaluation of an Explicit Approach

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-02
Start Date:
2022-02-15
Completion:
2027-07-31
Conditions
  • Developmental Language Disorder
  • Explicit Intervention
  • Grammatical Language
Interventions
  • BEHAVIORAL
No Results Yet
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