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Clinical Trials

Showing trials with last updates posted in 2026.

NCT05877599 | RECRUITING | PHASE1
45 participants

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-01
Start Date:
2023-07-12
Completion:
2029-07-31
Conditions
  • Non-small Cell Lung Cancer
  • Head and Neck Squamous Cell Carcinoma
  • Colorectal Carcinoma
  • Pancreatic Adenocarcinoma
  • Breast Cancer
  • Other Solid Tumors
  • Ovarian Cancer
  • Myeloid Neoplasms (AML/MDS)
Interventions
  • BIOLOGICAL
No Results Yet
NCT05773352 | ACTIVE_NOT_RECRUITING
118 participants

Perform® Humeral System - Fracture Study (PFX)

Study Type:
OBSERVATIONAL
Last Updated:
2026-09-01
Start Date:
2023-08-31
Completion:
2026-10-01
Conditions
  • Traumatic Arthropathy of Shoulder
  • Fracture Humerus
  • Traumatic Arthritis
  • Revision of Other Devices if Sufficient Bone Stock Remains
Interventions
  • DEVICE
No Results Yet
NCT05683184 | RECRUITING | PHASE1
30 participants

OMAR Opioid Use Disorder

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-01
Start Date:
2023-03-10
Completion:
2027-12-15
Conditions
  • Healthy Control
  • Opioid Use Disorder
Interventions
  • DRUG
No Results Yet
NCT05672316 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
28 participants

Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-01
Start Date:
2023-05-11
Completion:
2026-04-08
Conditions
  • Advanced Colorectal Adenocarcinoma
  • Advanced Microsatellite Stable Colorectal Carcinoma
  • Metastatic Colorectal Adenocarcinoma
  • Metastatic Microsatellite Stable Colorectal Carcinoma
  • Stage III Colorectal Cancer AJCC v8
  • Stage IV Colorectal Cancer AJCC v8
Interventions
  • BIOLOGICAL
  • PROCEDURE
  • DRUG
No Results Yet
NCT05668923 | RECRUITING | NA
600 participants

Speech Signals in Stuttering

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-01
Start Date:
2022-09-21
Completion:
2027-12-31
Conditions
  • Stuttering, Childhood
Interventions
  • BEHAVIORAL
No Results Yet
NCT05659953 | NOT_YET_RECRUITING | PHASE1
72 participants

LMT503 First-in-human SAD, MAD, and FE Study

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-01
Start Date:
2027-03-01
Completion:
2027-09-01
Conditions
  • Inflammatory Bowel Disease
  • Colitis, Ulcerative
  • Crohn Disease
Interventions
  • DRUG
No Results Yet
NCT05627635 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
20 participants

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-01
Start Date:
2023-05-03
Completion:
2027-06-16
Conditions
  • Metastatic Colon Adenocarcinoma
  • Metastatic Colorectal Adenocarcinoma
  • Metastatic Microsatellite Stable Colorectal Carcinoma
  • Metastatic Rectal Adenocarcinoma
  • Stage IV Colon Cancer AJCC v8
  • Stage IV Colorectal Cancer AJCC v8
  • Stage IV Rectal Cancer AJCC v8
Interventions
  • BIOLOGICAL
  • PROCEDURE
  • DRUG
No Results Yet
NCT05626855 | ACTIVE_NOT_RECRUITING | PHASE3
238 participants

Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-01
Start Date:
2023-04-17
Completion:
2026-11-01
Conditions
  • Spinal Muscular Atrophy
  • Spinal Muscular Atrophy Type 3
  • Spinal Muscular Atrophy Type 2
  • SMA
  • Neuromuscular Diseases
  • Muscular Atrophy
  • Atrophy
  • Muscular Atrophy, Spinal
  • Neuromuscular Manifestations
  • Anti-myostatin
Interventions
  • DRUG
No Results Yet
NCT05604430 | ENROLLING_BY_INVITATION
500 participants

Pre-hospital Ventilation Clinical Study

Study Type:
OBSERVATIONAL
Last Updated:
2026-09-01
Start Date:
2022-06-30
Completion:
2030-04-30
Conditions
  • Altered Mental Status
  • Sepsis
  • Heart Failure
  • Hemorrhage
  • Respiratory Distress Syndrome, Adult
  • Cardiac Arrest
Interventions
  • DEVICE
No Results Yet
NCT05538130 | ACTIVE_NOT_RECRUITING | PHASE1
148 participants

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-09-01
Start Date:
2022-11-30
Completion:
2027-08-31
Conditions
  • Melanoma
  • Glioma
  • Thyroid Cancer
  • Non-Small Cell Lung Cancer
  • Malignant Neoplasms
  • Brain Neoplasms
  • Advanced or Metastatic Solid Tumors
  • HGG
  • LGG
  • Low Grade Glioma
  • High Grade Glioma
  • Differentiated Thyroid Cancer
  • NSCLC (Non-small Cell Lung Cancer)
Interventions
  • DRUG
No Results Yet
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