Clinical Trials Updated in 2026

NCT04124029 | RECRUITING

800 participants

Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-07-01
Completion:: 2026-12-31

Conditions

Mild Traumatic Brain Injury
Moderate Traumatic Brain Injury
Mild Cognitive Impairment

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT04106349 | ACTIVE_NOT_RECRUITING

150 participants

Observational Real-life Study of Cabozantinib in Monotherapy or in Combination With Nivolumab in Advanced Renal Cell Carcinoma (RCC)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2020-03-03
Completion:: 2027-03-31

Conditions

Advanced or Metastatic Renal Cell Carcinoma

No Results Yet

NCT04086485 | RECRUITING | PHASE1/PHASE2

56 participants

Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-10-03
Completion:: 2027-07-01

Conditions

Gastroenteropancreatico Tumors
Neuroendocrine Tumors
Neuroendocrine Neoplasms

Interventions

DRUG
DIAGNOSTIC_TEST

No Results Yet

NCT04077086 | ACTIVE_NOT_RECRUITING | NA

10000 participants

Correcting Myopia Among Secondary School Children to Increase Academic High School Attendance Rates in Rural Communities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2024-11-28
Completion:: 2027-08-30

Conditions

Refractive Errors

Interventions

DEVICE

No Results Yet

NCT04034264 | RECRUITING

6500 participants

Febrile Disease Landscape in Cambodia Via Metagenomic Pathogen Sequencing

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-07-23
Completion:: 2027-07-01

Conditions

Vector-Borne Diseases
Emerging Pathogens

No Results Yet

NCT04014387 | COMPLETED | PHASE4

40 participants

Treatment of Disturbed Sleep in Progressive Supranuclear Palsy (PSP)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-06-02
Completion:: 2025-06-30

Conditions

Progressive Supranuclear Palsy(PSP)
Insomnia

Interventions

DRUG

No Results Yet

NCT04008706 | COMPLETED | PHASE3

552 participants

Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-09-17
Completion:: 2025-11-04

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG

Results Available

NCT03998254 | ACTIVE_NOT_RECRUITING | PHASE3

6000 participants

Efficacy, Immunogenicity and Safety of V503 in Chinese Women Aged 20-45 Years (V503-023)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-06-26
Completion:: 2028-03-31

Conditions

Papillomavirus Infections

Interventions

DRUG

No Results Yet

NCT03976843 | ACTIVE_NOT_RECRUITING | PHASE2

175 participants

Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-12-04
Completion:: 2027-11-19

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT03950076 | COMPLETED | PHASE4

948 participants

EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-09-20
Completion:: 2026-07-22

Conditions

Intracranial Hemorrhages
Atrial Fibrillation

Interventions

DRUG
OTHER

No Results Yet

NCT03937830 | ACTIVE_NOT_RECRUITING | PHASE2

27 participants

Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2021-03-10
Completion:: 2026-12-31

Conditions

Hepatocellular Cancer
Hepatocellular Carcinoma
Metastatic Hepatocellular Carcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03937817 | RECRUITING

300 participants

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-09-25
Completion:: 2029-03-31

Conditions

Alpha and Beta Thalassemia
Sickle Cell Disease
Malaria
Human Physiology

No Results Yet

NCT03937804 | COMPLETED

83 participants

New Approaches for Empowering Studies of Asthma in Populations of African Descent

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-09-23
Completion:: 2021-07-15

Conditions

Asthma

No Results Yet

NCT03929601 | ACTIVE_NOT_RECRUITING | PHASE2

74 participants

Rituximab-pvvr and Abatacept vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2023-10-30
Completion:: 2027-03-31

Conditions

Type 1 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT03922724 | ACTIVE_NOT_RECRUITING | PHASE2

91 participants

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-04-18
Completion:: 2027-06-01

Conditions

Peripheral T-cell Lymphomas
Lymphoproliferative Disorders
Immune System Diseases

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03911388 | RECRUITING | PHASE1

24 participants

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-09-12
Completion:: 2026-09-01

Conditions

Neoplasms, Brain
Glioblastoma Multiforme
Glioblastoma of Cerebellum
Neoplasms
Astrocytoma
Astrocytoma, Cerebellar
Neuroectodermal Tumors
Neuroectodermal Tumors, Primitive
Cerebellar PNET, Childhood
Cerebellar Neoplasms
Cerebellar Neoplasms, Primary
Cerebellar Neoplasm, Malignant
Cerebellar Neoplasm Malignant Primary
Neoplasm Metastases
Neoplasm Malignant
Neoplasms, Neuroepithelial
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Central Nervous System Neoplasms, Primary
Central Nervous System Neoplasms, Malignant
Nervous System Neoplasms
Neoplasms by Site
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Medulloblastoma Recurrent
HSV
Virus
Pediatric Brain Tumor
Nervous System Cancer
Primitive Neuroectodermal Tumor (PNET) of Cerebellum

Interventions

BIOLOGICAL

No Results Yet

NCT03910452 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

4 participants

Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-10-28
Completion:: 2034-06-15

Conditions

Chronic Granulomatous Disease

Interventions

DRUG
RADIATION
BIOLOGICAL

No Results Yet

NCT03900793 | RECRUITING | PHASE1

41 participants

Losartan + Sunitinib in Treatment of Osteosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-08-26
Completion:: 2027-08-01

Conditions

Osteosarcoma

Interventions

DRUG

No Results Yet

NCT03895645 | ENROLLING_BY_INVITATION

1000 participants

Connors Protocol for the Management and Use of Stored Human Specimens (Stored Human Specimens)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2026-09-06
Completion:: 2029-12-31

Conditions

Healthy Volunteer Samples

No Results Yet

NCT03886246 | ACTIVE_NOT_RECRUITING | PHASE2

131 participants

Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-05-29
Completion:: 2027-09-30

Conditions

Generalized Pustular Psoriasis

Interventions

DRUG

No Results Yet

NCT03867448 | RECRUITING

1000 participants

Study of Endocrine-Related Conditions and Physiology

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-03-27
Completion:: 2036-01-01

Conditions

Endocrine Disease

Interventions

DEVICE

No Results Yet

NCT03831958 | RECRUITING

600 participants

Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-03-04
Completion:: 2040-01-03

Conditions

Cushing Disease

No Results Yet

NCT03801434 | ACTIVE_NOT_RECRUITING | PHASE2

8 participants

Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-11-15
Completion:: 2029-02-28

Conditions

BCR-JAK2 Fusion Protein Expression
Blasts 20 Percent or Less of Peripheral Blood White Cells
Blasts More Than 5 Percent of Bone Marrow Nucleated Cells
Blasts More Than 5 Percent of Peripheral Blood White Cells
Blasts Under 20 Percent of Bone Marrow Nucleated Cells
Chronic Eosinophilic Leukemia, Not Otherwise Specified
Eosinophilia
Hepatomegaly
Hypereosinophilic Syndrome
JAK2 Gene Mutation
Splenomegaly
TEL-JAK2 Fusion Protein Expression

Interventions

DRUG

No Results Yet

NCT03773523 | ACTIVE_NOT_RECRUITING | NA

30 participants

Neuromodulation and Cognitive Training in Opioid Use Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-08-01
Completion:: 2027-05-15

Conditions

Opioid-use Disorder
Opioid Dependence
Opioid Abuse

Interventions

DEVICE

No Results Yet

NCT03766971 | SUSPENDED | PHASE2

160 participants

Influence of Tobacco Use on Cannabis Use

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2020-02-01
Completion:: 2027-11-30

Conditions

Cannabis Use
Tobacco Use

Interventions

BEHAVIORAL
DRUG

No Results Yet

NCT03762733 | ENROLLING_BY_INVITATION

500 participants

Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-01-04
Completion:: 2028-12-29

Conditions

Breast Cancer
Ovarian Cancer
Uterine Cancer

No Results Yet

NCT03755895 | COMPLETED | PHASE2

68 participants

Contribution of Hypnosis to Anxiety and Pain in Brachytherapy Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-11-02
Completion:: 2022-05-17

Conditions

Cancer
Brachytherapy

Interventions

OTHER
DRUG

No Results Yet

NCT03752697 | COMPLETED

30 participants

Metacognition in Neurological Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2018-12-13
Completion:: 2023-03-30

Conditions

Brain Injuries

Interventions

BEHAVIORAL

No Results Yet

NCT03739814 | RECRUITING | PHASE2

84 participants

Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-05-08
Completion:: 2027-02-01

Conditions

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Recurrent B Acute Lymphoblastic Leukemia
Refractory B Acute Lymphoblastic Leukemia

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT03733093 | COMPLETED

1377 participants

PREVAIL VIII: A CoHOrt Clinical, Viral, and ImmuNOlogic Monitoring Study of People Living With Retroviral Infection in Liberia (HONOR)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-08-22
Completion:: 2025-12-31

Conditions

HIV

No Results Yet

NCT03729115 | RECRUITING | NA

400 participants

A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-05-30
Completion:: 2028-12-31

Conditions

Breast Cancer

Interventions

PROCEDURE

No Results Yet

NCT03727555 | NOT_YET_RECRUITING | NA

30 participants

IT and IV Lentiviral Gene Therapy for X-ALD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2027-06-01
Completion:: 2028-05-31

Conditions

X-linked Adrenoleukodystrophy

Interventions

GENETIC

No Results Yet

NCT03725670 | NOT_YET_RECRUITING | NA

10 participants

Direct Lentiviral Injection Gene Therapy for MLD

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2027-05-31
Completion:: 2028-06-01

Conditions

Metachromatic Leukodystrophy (MLD)

Interventions

GENETIC

No Results Yet

NCT03678389 | RECRUITING | NA

70 participants

Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-05-09
Completion:: 2028-03-01

Conditions

Pituitary Neoplasm

Interventions

OTHER

No Results Yet

NCT03657394 | ACTIVE_NOT_RECRUITING | NA

3442 participants

Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2022-10-17
Completion:: 2025-09-01

Conditions

Hypoxic-Ischemic Encephalopathy
Birth Asphyxia

Interventions

OTHER

No Results Yet

NCT03648905 | COMPLETED

89 participants

Clinical Laboratory Evaluation of Chronic Autonomic Failure

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2018-09-06
Completion:: 2026-07-15

Conditions

Parkinson's Disease
Multiple System Atrophy
Autonomic Failure

Interventions

DRUG

No Results Yet

NCT03647878 | ACTIVE_NOT_RECRUITING

224 participants

Study of Cabozantinib as Monotherapy or in Combination With Nivolumab in Patients With Advanced or Metastatic Renal Cell Carcinoma Under Real-life Clinical Setting in 1st Line Treatment.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2018-09-24
Completion:: 2027-09-30

Conditions

Advanced Renal Cell Carcinoma
Metastatic Renal Cell Carcinoma

No Results Yet

NCT03604991 | SUSPENDED | PHASE2/PHASE3

278 participants

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2019-05-03
Completion:: 2026-12-31

Conditions

Clinical Stage II Esophageal Adenocarcinoma AJCC v8
Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage III Esophageal Adenocarcinoma AJCC v8
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Esophageal Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL
RADIATION

No Results Yet

NCT03600701 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-09-01
Start Date:: 2018-11-29
Completion:: 2025-07-14

Conditions

Metastatic Lung Non-Small Cell Carcinoma
Recurrent Lung Non-Small Cell Carcinoma
Refractory Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8

Interventions

DRUG
PROCEDURE

Results Available

NCT03581318 | RECRUITING

5000 participants

Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging

Study Type:: OBSERVATIONAL
Last Updated:: 2026-09-01
Start Date:: 2018-07-12
Completion:: 2028-04-01

Conditions

Normal and Abnormal Cardiovascular Physiology

No Results Yet