Clinical Trials

NCT07549490 | NOT_YET_RECRUITING | NA

25 participants

Human Experimental Models of Pain (HEMP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-03

Completion:

2029-12-31

Conditions

• Acute Pain

Interventions

• DRUG

No Results Yet

NCT07545122 | RECRUITING | PHASE1

162 participants

A Phase 1a/1b, First-Time-in-Human Study of CT-202, a Nectin-4 Directed Bispecific Antibody, in Participants With Recurring Triple Negative Breast, Colorectal, Urothelial Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-30

Completion:

2030-01-31

Conditions

• Triple Negative Breast Cancer (TNBC)
• Colorectal Cancer
• Urothelial Cancer

Interventions

• DRUG

No Results Yet

NCT07532889 | NOT_YET_RECRUITING | NA

430 participants

Comparing Medial and Lateral Dissection Approaches to the Recurrent Laryngeal Nerve During a Thyroidectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-30

Completion:

2028-10-31

Conditions

• Thyroidectomy

Interventions

• PROCEDURE

No Results Yet

NCT07524530 | NOT_YET_RECRUITING | PHASE2

102 participants

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-03

Completion:

2033-06-01

Conditions

• Core Binding Factor Alpha Subunits
• Hematologic Neoplasms
• Leukemia
• Lymphoma

Interventions

• DRUG
• RADIATION
• BIOLOGICAL

No Results Yet

NCT07520981 | COMPLETED

103 participants

Functional Capacity, Subjective Dyspnea and Fatigue in Smokers

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2026-04-15

Completion:

2026-07-30

Conditions

• Smoking

Interventions

• OTHER

No Results Yet

NCT07518901 | ENROLLING_BY_INVITATION | PHASE4

72 participants

Nanozymes in Endodontics

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-24

Completion:

2028-06-30

Conditions

• Apical Periodontitis
• Endodontic Disease
• Root Canal Infection

Interventions

• DRUG

No Results Yet

NCT07516093 | RECRUITING | PHASE3

620 participants

Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-03

Completion:

2029-10-31

Conditions

• B-cell Lymphoma
• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma

Interventions

• DRUG

No Results Yet

NCT07509034 | NOT_YET_RECRUITING | PHASE1

40 participants

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-03

Completion:

2030-01-30

Conditions

• Extensive-Stage Small Cell Lung Cancer
• Extrapulmonary Neuroendocrine Carcinoma
• Recurrent or Refractory
• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT07506616 | RECRUITING | PHASE1

24 participants

Membrane Potential Mapping with18F-TPP

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-31

Completion:

2033-08-31

Conditions

• Membrane Potential Mapping

Interventions

• DRUG

No Results Yet

NCT07504601 | NOT_YET_RECRUITING | PHASE2

92 participants

Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-03

Completion:

2030-12-31

Conditions

• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT07503379 | RECRUITING | PHASE2

109 participants

Evaluation of the Efficacy and Safety of Darolutamide + ADT Combined With Low-dose Docetaxel in mHSPC

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-04-16

Completion:

2027-12-31

Conditions

• mHSPC

Interventions

• DRUG

No Results Yet

NCT07498517 | RECRUITING | PHASE2

90 participants

Safety and Efficacy of a Single Dose of Gruticibart to Prevent CRT

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-06

Completion:

2029-02-02

Conditions

• Thrombosis

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT07490379 | RECRUITING | NA

66 participants

Comparison of the Efficacy of Transcranial Direct Current Stimulation at Home Versus in Hospital Settings in Patients With Depressive Episodes

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-07-31

Completion:

2028-03-31

Conditions

• Depression

Interventions

• OTHER

No Results Yet

NCT07490301 | RECRUITING | PHASE2/PHASE3

900 participants

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-04-30

Completion:

2031-06-30

Conditions

• Metastatic Pancreatic Ductal Adenocarcinoma
• PDAC

Interventions

• DRUG

No Results Yet

NCT07489378 | RECRUITING

4000 participants

NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-03

Completion:

2035-04-01

Conditions

• Very Rare Tumors
• Very Rare Cancers
• Other Solid Tumors
• Solid Tumor
• Pediatric Rare Tumors

Interventions

• OTHER

No Results Yet

NCT07486518 | RECRUITING

4000 participants

A Multicentre Observational Cross-Sectional Study of The Gastric Precancerous Epithelial Pathway Using High-Definition Endoscopy And Histopathology In India

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-01

Completion:

2028-04-01

Conditions

• Gastric Adenocarcinoma
• Early Gastric Cancer

No Results Yet

NCT07485569 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-01

Completion:

2027-09-01

Conditions

• Thyroid Cancer Stage IV
• Anaplastic Thyroid Cancer
• Differentiated Thyroid Cancer
• Poorly Differentiated Thyroid Carcinoma

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT07484139 | NOT_YET_RECRUITING | PHASE2

26 participants

H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-30

Completion:

2028-05-31

Conditions

• Oral Cavity Squamous Cell Carcinoma
• Head and Neck Cancer

Interventions

• DRUG

No Results Yet

NCT07479979 | RECRUITING | PHASE1/PHASE2

62 participants

Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-05-21

Completion:

2027-07-31

Conditions

• Relapse Multiple Myeloma
• Refractory Multiple Myeloma

Interventions

• DRUG
• DEVICE

No Results Yet

NCT07479953 | NOT_YET_RECRUITING | PHASE1

5 participants

Prenatal Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2027-01-01

Completion:

2039-06-01

Conditions

• GM1 Gangliosidoses
• GM1 Gangliosidosis, Type I
• GM1 Gangliosidosis, Type 2

Interventions

• DRUG

No Results Yet

NCT07478991 | RECRUITING | PHASE3

376 participants

Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients (VENP-A-QUI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-07-02

Completion:

2030-04-30

Conditions

• Acute Myeloid Leukemia, Adult

Interventions

• DRUG

No Results Yet

NCT07475949 | NOT_YET_RECRUITING | PHASE3

352 participants

Unknown Time of Onset Stroke RePerfusIon Without Advanced Imaging

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-30

Completion:

2028-12-31

Conditions

• Acute Ischemic Stroke
• Tenecteplase

Interventions

• DRUG
• OTHER

No Results Yet

NCT07475936 | RECRUITING

392 participants

Intravenous Tenecteplase in Very Old Patients With Acute Ischemic Stroke

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2026-03-22

Completion:

2027-12-31

Conditions

• Acute Ischemic Stroke
• Tenecteplase

Interventions

• DRUG
• OTHER

No Results Yet

NCT07475273 | COMPLETED | NA

66 participants

The Effectiveness of Early Mobilisation on Back Pain in Patients Following Percutaneous Coronary Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-03-30

Completion:

2026-05-30

Conditions

• Coronary Artery Disease

Interventions

• OTHER

No Results Yet

NCT07472205 | NOT_YET_RECRUITING | NA

70 participants

Foot and Ankle Strengthening Program to Improve Physical Function in Menopausal Women (FAMEX)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-01

Completion:

2027-01-15

Conditions

• Menopause
• Musculoskeletal Function
• Physical Function

Interventions

• OTHER

No Results Yet

NCT07471139 | NOT_YET_RECRUITING | PHASE3

460 participants

SWITCH: Apixaban vs Vitamin K in HM3

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-31

Completion:

2029-08-31

Conditions

• LVAD (Left Ventricular Assist Device) Thrombosis
• Heart Failure
• Bleeding
• Thrombosis; Artery
• Stroke
• Heart Transplant

Interventions

• DRUG

No Results Yet

NCT07470983 | RECRUITING | PHASE2

60 participants

A Phase II Clinical Study on the Efficacy and Safety of HRS-1780 in Participants With Primary Aldosteronism

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-04-23

Completion:

2026-11-30

Conditions

• Primary Aldosteronism

Interventions

• DRUG

No Results Yet

NCT07469124 | ACTIVE_NOT_RECRUITING | NA

55 participants

Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2025-12-01

Completion:

2027-01-31

Conditions

• Molar Incisor Hypomineralization

Interventions

• PROCEDURE

No Results Yet

NCT07468071 | RECRUITING | PHASE1/PHASE2

40 participants

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-06-08

Completion:

2029-06-11

Conditions

• Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung Cancer
• Advanced Solid Tumors Harboring the KRAS G12C Mutation

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT07466498 | NOT_YET_RECRUITING | PHASE2

60 participants

Estrogen to Improve Quality of Life for Men With Newly Diagnosed or Recurrent Metastatic Hormone Sensitive Prostate Cancer, EQUIP Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-11-01

Completion:

2029-06-01

Conditions

• Castration-Sensitive Prostate Adenocarcinoma
• Metastatic Castration-Sensitive Prostate Adenocarcinoma
• Stage IVB Prostate Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL
• OTHER

No Results Yet

NCT07463963 | RECRUITING | NA

2600 participants

Relevance of the Urine Bacterial Culture Performed Before TransUrethral Resection of the Bladder for Post-operative Febrile Urinary Tract Infections Prevention: a Non-inferiority Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-06-29

Completion:

2030-07-29

Conditions

• Bladder Cancer
• Transurethral Resection of the Bladder
• Urinary Tract Infection Bacterial

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT07463183 | RECRUITING | PHASE2

100 participants

A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-03-24

Completion:

2027-10-28

Conditions

• Colitis Ulcerative
• Ulcerative Colitis

Interventions

• DRUG
• OTHER

No Results Yet

NCT07460986 | RECRUITING | PHASE1/PHASE2

278 participants

A Phase Ib/II Study to Evaluate Safety and Efficacy of Bexmarilimab in Combination With Doxorubicin in Metastatic Soft-tissue Sarcoma.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-20

Completion:

2028-07-31

Conditions

• Soft Tissue Sarcoma (STS)

Interventions

• DRUG

No Results Yet

NCT07452692 | ACTIVE_NOT_RECRUITING | PHASE1

232 participants

A Study to Assess the Skin Irritation and Sensitization of Selegiline TDS in Healthy Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-08-23

Completion:

2026-10-06

Conditions

• Major Depressive Disorder (MDD)

Interventions

• DRUG

No Results Yet

NCT07439380 | RECRUITING | NA

1110 participants

Group-Care for Hypertension and Diabetes Management in Nepal

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-07-29

Completion:

2027-08-31

Conditions

• Hypertension
• Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT07437976 | NOT_YET_RECRUITING

400 participants

A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-03

Completion:

2036-12-23

Conditions

• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT07437950 | RECRUITING | PHASE2

126 participants

Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2027-04-18

Completion:

2034-09-22

Conditions

• Acute Myeloid Leukemia

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT07437313 | NOT_YET_RECRUITING | NA

100 participants

Marine Lipids Ease Painful TMD

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-09-25

Completion:

2030-01-31

Conditions

• Temporomandibular Disorder (TMD)

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT07435220 | NOT_YET_RECRUITING | NA

100 participants

Robot-Assisted Meditation for Older Adults With Cognitive Concerns

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-31

Start Date:

2026-11-01

Completion:

2027-10-31

Conditions

• Cognitive Impairment
• Perceived Stress

Interventions

• BEHAVIORAL

No Results Yet

NCT07424261 | RECRUITING

125 participants

NIS to Examine Disease Activity in SLE Patients Treated With Subcutaneous Anifrolumab in Routine Care

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-31

Start Date:

2026-03-19

Completion:

2029-08-31

Conditions

• Lupus Erythematosus, Systemic

No Results Yet